Description
4-Methoxyphenylhydrazine hydrochloride is a kind of midbody that is mainly used for producing phenylhydrazine, and can also be used to make other Chemicals. The reparation technology of 4-Methoxyphenylhydrazine hydrochloride comprises aniline diazonium and benzene diazonium chloride diazo benzene chloride two-step process.
Chemical Properties
slightly pink to greyish-purple powder
Uses
4-Methoxyphenylhydrazine hydrochloride was used in the preparation of 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1,2,4-thiadiazole.
Synthesis
4-Methoxyphenylhydrazine hydrochloride Preparation Process: Take hydrochloric acid and sodium nitrite and add them sequentially to aniline, where the molar ratio of aniline to hydrochloric acid to sodium nitrite is 1:2.3 to 3.2:1 to 1.1, and sodium nitrite is added at 0 to 5°C. The reaction temperature is 0 to 22°C, and the reaction time is 30 to 90 minutes. Then add ammonium sulfite and hydrochloric acid according to a molar ratio to aniline of 1:2 to 3.5:2.5 to 3.0. After reduction, hydrolysis, and acidification, the product can be obtained by filtration or centrifugation.
