Chemical Properties
white to light yellow crystal powde
Uses
1-Acetyl-2-phenylhydrazine is an Anaerobically curable compound.
Synthesis Reference(s)
The Journal of Organic Chemistry, 30, p. 2486, 1965
DOI: 10.1021/jo01018a525
General Description
Colorless prisms or white solid.
Air & Water Reactions
Water insoluble.
Reactivity Profile
1-Acetyl-2-phenylhydrazine is an amide and an amine. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition 1-Acetyl-2-phenylhydrazine emits toxic fumes.
Fire Hazard
Flash point data for 1-Acetyl-2-phenylhydrazine are not available. 1-Acetyl-2-phenylhydrazine is probably combustible.
Biological Activity
1-Acetyl-2-phenylhydrazine (AcPhHZ) is a vascular tumor initiator used in experimental animal model.
Purification Methods
Crystallise the hydrazine from aqueous EtOH. [Beilstein 15 H 241.]
