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4-Methoxyphenol

4-Methoxyphenol Structure
4-Methoxyphenol
  • CAS No.150-76-5
  • Chemical Name:4-Methoxyphenol
  • CBNumber:CB7853133
  • Molecular Formula:C7H8O2
  • Formula Weight:124.14
  • MOL File:150-76-5.mol
4-Methoxyphenol Property
  • Melting point: :56 °C
  • Boiling point: :243 °C(lit.)
  • Density  :1,55 g/cm3
  • vapor density  :4.3 (vs air)
  • vapor pressure  :<0.01 mm Hg ( 20 °C)
  • refractive index  :1.5286 (estimate)
  • Flash point: :>230 °F
  • storage temp.  :Refrigerator
  • solubility  :Soluble in acetone, ethyl acetate, ethanol, ether, benzene and carbon tetrachloride.
  • form  :Liquid
  • pka :10.21(at 25℃)
  • color  :Clear colorless to pale yellow
  • PH :5.1 (30g/l, H2O, 20℃)
  • Odor Threshold :0.0027ppm
  • Water Solubility  :40 g/L (25 ºC)
  • BRN  :507924
  • Stability: :Stable. Combustible. Incompatible with halogens, oxidizing agents.
  • InChIKey :NWVVVBRKAWDGAB-UHFFFAOYSA-N
  • Indirect Additives used in Food Contact Substances :4-METHOXYPHENOL
  • CAS DataBase Reference :150-76-5(CAS DataBase Reference)
  • FDA 21 CFR :177.1010
  • EWG's Food Scores :4-7
  • FDA UNII :6HT8U7K3AM
  • NIST Chemistry Reference :Mequinol(150-76-5)
  • EPA Substance Registry System :p-Methoxyphenol (150-76-5)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H402-H302-H317-H319-H361d-H412
  • Precautionary statements P201-P273-P280-P308+P313-P333+P313-P337+P313-P261-P264-P270-P272-P301+P312+P330-P302+P352+P333+P313+P363-P305+P351+P338+P337+P313-P501-P262-P280a-P301+P310-P305+P351+P338-P315
4-Methoxyphenol Price More Price(24)
  • Brand: Sigma-Aldrich
  • Product number: 8.21233
  • Product name : 4-Methoxyphenol
  • Purity: for synthesis
  • Packaging: 5 g
  • Price: $17.2
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 8.21233
  • Product name : 4-Methoxyphenol
  • Purity: for synthesis
  • Packaging: 25 g
  • Price: $22.01
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 54050
  • Product name : 4-Methoxyphenol
  • Purity: purum, ≥98.0% (HPLC)
  • Packaging: 100g
  • Price: $31.4
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 8.21233
  • Product name : 4-Methoxyphenol
  • Purity: for synthesis
  • Packaging: 250 g
  • Price: $39.5
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 54050
  • Product name : 4-Methoxyphenol
  • Purity: purum, ≥98.0% (HPLC)
  • Packaging: 500g
  • Price: $63.2
  • Updated: 2021/03/22
  • Buy: Buy

4-Methoxyphenol Chemical Properties,Usage,Production

  • Chemical Properties White crystals.
  • Chemical Properties 4-Methoxyphenol is a colorless to white, waxy solid with an odor of caramel and phenol. A combustible solid.
  • Uses Inhibitor for acrylic monomers; stabilizer for chlorinated hydrocarbons and ethyl cellulose; UV inhibitor
  • Uses Intermediates of Liquid Crystals
  • Uses 5HT1&2 receptor antagonist.
    Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts as a competitive inhibitor of melanogenesis.
  • Indications Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts as a competitive inhibitor of melanogenesis.
  • Synthesis Reference(s) The Journal of Organic Chemistry, 42, p. 1479, 1977 DOI: 10.1021/jo00428a054
    Synthesis, p. 751, 1983 DOI: 10.1055/s-1983-30501
    Tetrahedron Letters, 34, p. 7667, 1993 DOI: 10.1016/S0040-4039(00)61534-4
  • General Description Pink crystals or white waxy solid.
  • Air & Water Reactions Sensitive to moisture. Water soluble.
  • Reactivity Profile 4-Methoxyphenol can react with oxidizing materials.
  • Hazard Eye irritant and skin damage.
  • Health Hazard 4-Methoxyphenol is expected to cause liver and renal toxicity with narcosis, but only at high levels of exposure.
  • Fire Hazard Combustible
  • Safety Profile Poison by intraperitoneal route. A skin irritant. When heated to decomposition it emits acrid smoke and fumes. See also ETHERS.
  • Shipping UN3335 Aviation regulated solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.
  • Purification Methods Crystallise 4-methoxyphenol from *benzene, pet ether or H2O, and dry it under vacuum over P2O5 at room temperature. Sublime it in vacuo. [Wolfenden et al. J Am Chem Soc 109 463 1987, Beilstein 6 IV 5717.]
4-Methoxyphenol Preparation Products And Raw materials
Raw materials
Preparation Products
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