Description
N
6-Methyladenosine 5''-monophosphate is an activator of glycogen phosphorylase
b (K
a = 22 μM). It is also a non-competitive inhibitor of rat adenylate kinase II (K
i = 4.2 mM). N
6-Methyladenosine 5’-monophosphate (sodium salt) has been used for immunoprecipitation of N
6-methyladenosine.
Chemical Properties
White to off-white free flowing powder
Uses
N6-Methyladenosine 5′-monophosphate sodium salt can be used in
N6-methyladenosine (m
6A) ribonucleoprotein immunoprecipitation reactions. m6A has gained a lot of attention in the recent years because the mRNA modification with m6A has been shown to play a role in stability and translational efficiency of mRNA.
Uses
N6-Methyladenosine-5''-monophosphate Sodium Salt is used in method for improving the yield of m6A antibody enriched methylated mRNA.
Biochem/physiol Actions
A glycogen phosphorylase b activator.
