Uses
Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.
As a flavor ingredient
Identification
CAS.No.:
13474-03-8
FL.No.:
n/a
FEMA.No.:
4224
NAS.No.:
n/a
CoE.No.:
n/a
EINECS.No.:
JECFA.No.:
n/a
CoE: n/a
FDA: n/a
FDA (other): n/a
JECFA: n/a
Reported uses (ppm): (FEMA, 2005)
Alcoholic beverages
300
800
Breakfast cereals
300
800
Condiments, relishes
400
800
Instant coffee, tea
300
800
Nonalcoholic beverages
300
800
Processed vegetables
400
800
Reconstituted vegetables
400
800
Seasonings, flavors
400
900
Sugar substitutes
400
800
Not reported found in nature.
Uses
Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].
References
[1] Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287(8):5301-9. DOI:
10.1074/jbc.M111.291666[2] Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985. DOI:
10.1038/cddis.2013.516[3] Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3(3):161-74. DOI:
10.1016/0166-3542(83)90023-2
