Description
NADP+ is a coenzyme that is widely distributed in living matter, Participates in oxidation-reduction reactions. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH).
NADP is a substance in which nicotinic acid amide adenine dinucleotide and a phosphate molecule are bound by ester bond. It is a hydrogen receptor and can be used for the development and development of a variety of in vitro diagnostic reagents. Prepared in large quantities.
Chemical Properties
Yellowish powder
Uses
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
Uses
Disodium NADP is used in method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.
Application
A participant coenzyme in aerobic and anaerobic oxidation
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
General Description
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions
in vivo.
Mechanism of action
β-Nicotinamide adenine dinucleotide NAD and β-nicotinamide adenine dinucleotide phosphate NADP are coenzymes necessary for cellular energy metabolism and play a central role in energy metabolism. In addition, purine nucleotides also play an important transfer role in biological processes. Protons in energy reactions are usually first transferred to NAD and NADP, then reduced to NADH and NADPH, and transferred to oxygen through electrons to release energy. The generated reduced NADH and NADPH are coenzymes of glutathione reductase and have important antioxidant functions.
Biotechnological Applications
Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. The NADPH/NADP ratio regulates the intracellular redox potential, thereby influencing metabolic reactions in vivo. The β-NADH phosphate disodium salt has been used for the quantification of glucose in glycogen. It has also been used for the hexokinase assay.
Precautions
Protect from light and moisture. Keep cool and dry. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Store under inert gas.
