General Description
4-Amino-3-phenyl-butyric acid hydrochloride is a derivative of γ-Aminobutyric Acid which possesses neuroprotective activity. It is an organic compound characterized by the presence of both a carboxylic acid and an amine group. It′s an amino acid and holds substantial importance in the fields of biochemistry and physiology. Its versatile nature allows for a broad spectrum of applications in scientific research, particularly in studies involving enzyme inhibition and receptor activation.
Synthesis
GENERAL METHOD: 4-phenyl-2-pyrrolidone (0.4 mmol) and 10 mL of HCl (6.0 mol/L) were added to a round bottom flask. The reaction mixture was magnetically stirred under reflux conditions for 12 hours. After completion of the reaction, the solvent was removed by evaporation under reduced pressure to give 3-phenyl-4-aminobutyric acid hydrochloride.
References
[1] New Journal of Chemistry, 2015, vol. 39, # 3, p. 1643 - 1653
[2] Journal of the Brazilian Chemical Society, 2017, vol. 28, # 2, p. 285 - 298
[3] RSC Advances, 2014, vol. 4, # 5, p. 2538 - 2545
