Uses
Iso-Forskolin is a byproduct in the synthesis of 9-Deoxyforskolin (D239935) from Coleus forskohlii, which is an adenylyl cyclase isoform activator; Antihypertensive.
Uses
6-Acetyl-7-deacetylforskolin is a bioactive constituents from the medical plant, Coleus forskohlii. Also, it has anticancer and glucosidase inhibition activities.
General Description
This substance is supplied with certified chromatographic purity. The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biological Activity
Isoforskolin is a naturally occurring diterpene with anti-inflammatory activity. It has been shown to downregulate the expression of proinflammatory compounds. In an experimental mouse model of Lyme Disease induced arthritis isoforskolin downregulated the transcription and expression of TNF-α and IL-6 induced by recombinant Borrelia burgdorferi basic membrane protein A (rBmpA). In a r at asthmatic model isoforskolin down-regulated production of transforming growth factor β1 (TGF-β1) and interleukin-1β (IL-1β) which was accompanied by inhibition of inflammation and airway remodeling.
