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Parthenolide

Parthenolide Structure
Parthenolide
  • CAS No.20554-84-1
  • Chemical Name:Parthenolide
  • CBNumber:CB0446848
  • Molecular Formula:C15H20O3
  • Formula Weight:248.32
  • MOL File:20554-84-1.mol
Parthenolide Property
  • Melting point: :115-116 °C (lit.)
  • alpha  :D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)
  • Boiling point: :394.1±42.0 °C(Predicted)
  • Density  :1.13±0.1 g/cm3(Predicted)
  • storage temp.  :-20°C
  • form  :White solid
  • Merck  :14,7048
  • CAS DataBase Reference :20554-84-1
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Parthenolide Price More Price(9)
  • Brand: Sigma-Aldrich
  • Product number: 512732
  • Product name : Parthenolide
  • Purity: 
  • Packaging: 50mg
  • Price: $74.92
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 1500400
  • Product name : Parthenolide
  • Purity: United States Pharmacopeia (USP) Reference Standard
  • Packaging: 25mg
  • Price: $176
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: P1982
  • Product name : Parthenolide
  • Purity: >97.0%(HPLC)
  • Packaging: 25mg
  • Price: $83
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: TCI Chemical
  • Product number: P1982
  • Product name : Parthenolide
  • Purity: >97.0%(HPLC)
  • Packaging: 100mg
  • Price: $247
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 70080
  • Product name : Parthenolide
  • Purity: ≥98%
  • Packaging: 50mg
  • Price: $54
  • Updated: 2021/03/22
  • Buy: Buy

Parthenolide Chemical Properties,Usage,Production

  • Description Parthenolide is an allergen in feverfew (Tanacetum parthenarium).
  • Chemical Properties White solid
  • Uses Antiinflammatory;MAP kinase inhibitor
  • Uses Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium). It inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml). Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription. This compound has also been shown to block inflammation by inhibiting signaling through NF-κB. Inhibition of NF-κB by parthenolide can be achieved by direct binding of the pattern recognition receptor NOD2 by parthenolide.
  • Definition ChEBI: A sesquiterpene lactone and active principle of Feverfew (Tanacetum parthenium).
  • Biological Activity The active principle of feverfew (Chrysanthemum parthenium), widely used as a herbal remedy for arthritis and migraine and as a febrifuge. Parthenolide is antisecretory, anti-inflammatory, spasmolytic and inhibits the release of 5-HT from blood platelets. Also inhibits generation of leukotriene B 4 and thromboxane B 2 .
  • Contact allergens Parthenolide is a sesquiterpene lactone found Asteraceae- Compositae such as feverfew (Tanacetum parthenium Schultz-Bip.) or congress grass (Parthenium hysterophorus L.).
Parthenolide Preparation Products And Raw materials
Raw materials
Preparation Products
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20554-84-1, ParthenolideRelated Search:
  • Parthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem
  • Factory Price Parthenolide 20554-84-1
  • Natural Plant Extracts Parthenolide 20554-84-1 High Purity HPLC>98%
  • Feverfew P.E Parthenlide
  • [1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • (1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one
  • 4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic acid γ-lactone
  • 4,5alpha-epoxy-6beta-hydroxy-germacra-1(10),11(13)-dien-12-oic acid gamma-lactone
  • Germacra-1(10),11(13)-dien-12-oic acid, 4,5-alpha-epoxy-6-beta-hydroxy-, gamma-lactone
  • Parthenolide
  • Parthenolide ((-)-Parthenolide)
  • PartheNAlide
  • Aids007764
  • Aids-007764
  • Nsc157035
  • Oxireno[9,10]cyclodeca[1,2-B]furan-9(1ah)-one, 2,3,6,7,7A,8,10A,10B-octahydro-1A,5-dimethyl-8-methylene-, (1ar,4E,7as,10as,10bs)-
  • Parthenolides
  • Parthelide
  • Parthenolide (25 mg)
  • Oxireno(9,10)cyclodeca(1,2-B)furan-9(1ah)-o
  • Parthenolide, froM ChrysantheMuM MorifoliuM
  • (3aS,9aR,10aS,10bS,E)-6,9a-dimethyl-3-methylene-3a,4,5,8,9,9a,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-2(3H)-one
  • PTL
  • Parthenolide(PTL)
  • [1AR-(1AR*,4E,7AS*,10AS*-10BR*)]-2,3-6,7,7A,8,10A,10B-OCTAHYDRO-1A,5-DIMETHYL-8-METHYLENEOXIRENO[9,10]CYCLODECA[1,2-B]FURAN-9(1AH)-ONE
  • PARTHENOLIDE, TANACETUM PARTHENIUM
  • 4,5-alpha-epoxy-6-beta-hydroxy-11(13)-dien-12-oicacigamma-germacra-1(10
  • 4,5-alpha-epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oicacidgamma-la
  • Parthenolide from Chrysanthenum parthenium
  • Oxireno9,10cyclodeca1,2-bfuran-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-
  • Parthenolide, 98%, from Chrysanthemum morifolium
  • Parthenolide&gt
  • (-)-Parthenolide
  • PARTHENOLIDE, DIMETHYLAMINOPARTHENOLIDE
  • parthenolider
  • 20554-84-1
  • 10-21-7
  • 20552-41-8
  • Anti-Proliferative Agents
  • Antitumor Agents
  • BioChemical
  • Cancer Research
  • inhibitor
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Natural Product
  • Sesqui-Terpenoids
  • Isoprenoid/terpenoidNeurotransmitters
  • Anti-Proliferative AgentsNutrition Research
  • Antitumor Agents
  • Biochemicals Found in Plants
  • Cancer Research
  • Others
  • Serotonergics
  • Prostanoid receptor and related