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Riboflavine Structure

Riboflavine

Chemical Properties

Melting point 290 °C (dec.)(lit.)
alpha  -135 º (c=5, 0.05 M NaOH)
Boiling point 504.93°C (rough estimate)
Density  1.2112 (rough estimate)
refractive index  -135 ° (C=0.5, JP Method)
Flash point 9℃
storage temp.  2-8°C
solubility  Very slightly soluble in water, practically insoluble in ethanol (96 per cent). Solutions deteriorate on exposure to light, especially in the presence of alkali. It shows polymorphism (5.9).
form  Powder
pka 1.7(at 25℃)
color  Yellow to orange
PH 5.5-7.2 (0.07g/l, H2O, 20°C)
Odor Slight odour
PH Range 6
Water Solubility  0.07 g/L (20 ºC)
Sensitive  Light Sensitive
Merck  14,8200
BRN  97825
BCS Class 1
Stability Stable, but light-sensitive. Incompatible with strong oxidizing agents, reducing agents, bases, calcium, metallic salts. May be moisture sensitive.
InChIKey AUNGANRZJHBGPY-SCRDCRAPSA-N
LogP -2.009 (est)
FDA 21 CFR 184.1695; 582.5695; 73.450; 101.9; 104.20; 107.10; 107.100; 136.115; 137.165; 137.185; 310.545
Substances Added to Food (formerly EAFUS) RIBOFLAVIN
SCOGS (Select Committee on GRAS Substances) Riboflavin
CAS DataBase Reference 83-88-5(CAS DataBase Reference)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms riboflavin; vitamin B2
FDA UNII TLM2976OFR
NCI Drug Dictionary riboflavin
ATC code S01XA26
NIST Chemistry Reference Riboflavine(83-88-5)
EPA Substance Registry System Riboflavin (83-88-5)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H226-H301+H311+H331-H370
Precautionary statements P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  24/25-45-36/37-16
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  1
RTECS  VJ1400000
8-10-21
TSCA  Yes
HS Code  29362300
Hazardous Substances Data 83-88-5(Hazardous Substances Data)
Toxicity LD50 in rats (g/kg): >10 orally, 5.0 s.c., 0.56 i.p. (Unna, Greslin)
NFPA 704:
0
1 0

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