Kaliumthioacetat

Bezeichnung:Kaliumthioacetat

CAS-Nr10387-40-3

Englisch Name:Potassium thioacetate

CBNumberCB9316520

SummenformelC2H3KOS

Molgewicht114.21

MOL-Datei10387-40-3.mol

Synonyma

Kaliumthioacetat

Kaliumthioacetat physikalisch-chemischer Eigenschaften

Schmelzpunkt	173-176 °C (lit.)
Dichte	1.58 g/cm3
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	soluble
Aggregatzustand	Crystalline Powder, Crystals or Chunks
Farbe	White to light brown
Wasserlöslichkeit	soluble
Sensitive	Air Sensitive & Hygroscopic
Hydrolytic Sensitivity	4: no reaction with water under neutral conditions
BRN	3595448
CAS Datenbank	10387-40-3(CAS DataBase Reference)
EPA chemische Informationen	Ethanethioic acid, potassium salt (10387-40-3)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37/39
RIDADR	UN 3335
WGK Germany	3
F	3-9-13-23
TSCA	Yes
HazardClass	9
HS Code	29309070

Gefahreninformationscode (GHS)

Potassium thioacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white to light brown crystalline powder, crystals
Verwenden
Potassium Thioacetate is the potassium salt of Thioacetic Acid, a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.
Verwenden
Potassium thioacetate is used for palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives. It is also used as a reagent in the conversion of halides to thiols.
Application
Potassium thioacetate is an organosulfur compound and a salt with the formula CH3COS−K+. This white, water-soluble solid is used as a reagent for preparing thioacetate esters and other derivatives . It acts as a sulfur source in the synthesis of sulfur-containing organic compounds for the synthesis of heterocycles, polymers, transition-metal ligands, nanoparticles, bioactive compounds and macromolecular inclusion complexes. It is also used for palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives and it is also used as a reagent in the conversion of halides to thiols.
Reaktionen
Thioacetate is also a class of sulfur-containing nucleophiles, of which potassium thioacetate is the most widely used reagent. Potassium thioacetate reacts with organic halides to form thioesters, which are often used as thiol-protecting groups.In the classical reaction, potassium thioacetate replaces the bromine atom to form a thiol in which the thioester formed in the first step is subjected to a nucleophilic addition elimination reaction to obtain a thiol via hydrolysis, alcoholysis or ammonolysis. Unlike the thiol formation from bromine and thiourea, this method is not strictly limited to polystyrenes. It can also be extended to poly(meth)acrylate systems. It is important that there is no observation of ester hydrolysis during the process.

Potassium thioacetate Upstream-Materialien And Downstream Produkte

Kaliumthioacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

10387-40-3, Potassium thioacetate Verwandte Suche:

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