2-Thiobarbitursure

Bezeichnung:2-Thiobarbitursure

CAS-Nr504-17-6

Englisch Name:2-Thiobarbituric acid

CBNumberCB5251676

SummenformelC4H4N2O2S

Molgewicht144.15

MOL-Datei504-17-6.mol

Synonyma

2-Thiobarbitursure

2-Thiobarbitursure physikalisch-chemischer Eigenschaften

Schmelzpunkt	245 °C (dec.)(lit.)
Dichte	1.451 (estimate)
Brechungsindex	1.7690 (estimate)
storage temp.	Inert atmosphere,2-8°C
Löslichkeit	50g/l slightly soluble
Aggregatzustand	Liquid
pka	3.96±0.20(Predicted)
Farbe	Clear colorless
PH	1.7-1.9 (10g/l, H2O, 20℃)
Wasserlöslichkeit	<6 g/L (20 ºC)
BRN	120663
Stabilität	Stable. Incompatible with strong oxidizing agents.
InChIKey	RVBUGGBMJDPOST-UHFFFAOYSA-N
CAS Datenbank	504-17-6(CAS DataBase Reference)
NIST chemische Informationen	4,6(1H,5h)-pyrimidinedione, dihydro-2-thioxo-(504-17-6)
EPA chemische Informationen	4,6(1H,5H)-Pyrimidinedione, dihydro-2-thioxo- (504-17-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	22-24/25-37/39-26
RIDADR	UN 3335
WGK Germany	2
RTECS-Nr.	CQ7700000
F	13-23
TSCA	Yes
HS Code	29335995

Gefahreninformationscode (GHS)

2-Thiobarbituric acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Off-White to Yellow Powder. soluble in hot water, alcohol, ether, alkali and sodium carbonate solution, slightly soluble in water.
Verwenden
2-Thiobarbituric acid has been used to measure malondialdehyde (MDA) in lipid peroxidation assay.
Verwenden
4,6-Dihydroxy-2-mercaptopyrimidine can be used to quantitate lipopolysaccharides, carrageenan, and sialic acids, and to detect lipid hydroperoxides and lipid oxidation.
Definition
ChEBI: 2-thiobarbituric acid is a barbiturate, the structure of which is that of barbituric acid in which the oxygen at C-2 is replaced by sulfur. It has a role as a reagent and an allergen.
synthetische
2-thiobarbituric acid was synthesized by the reaction of diethyl malonate with thiourea. Dissolve thiourea in methanol, add sodium methoxide and diethyl malonate, heat under reflux for 4-5h, then distill under reduced pressure to recover methanol to the end, and add hydrochloric acid to acidify to pH 1-2 after cooling. After standing overnight, thiobarbituric acid crystals were precipitated, filtered, and recrystallized with water to obtain the pure product.
Allgemeine Beschreibung
2-Thiobarbituric acid is a molecule made up of heteroatoms: nitrogen, sulphur and oxygen.
Biochem/physiol Actions
2-Thiobarbituric acid (TBA) is useful to quantitate lipopolysaccharides, carrageenan, and sialic acids. It is also used to detect lipid hydroperoxides and lipid oxidation. It has applications in the field of medicine and biochemistry. TBA may possess the ability to prevent metal corrosion.
läuterung methode
Crystallise it from water. [Beilstein 24 H 476, 24 I 414, 24 II 275, 24 III/IV 1884.]

2-Thiobarbituric acid Upstream-Materialien And Downstream Produkte

2-Thiobarbitursure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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