2-(3,6-Dihydroxy-2,4,5,7-tetrabromxanthen-9-yl)-benzoesure

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P271：Nur im Freien oder in gut belüfteten Räumen verwenden.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Solvent Red 43 Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R36:Reizt die Augen.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

• Chemische Eigenschaften

  orange-brown powder

• Verwenden

  Eosin Acid C.I. No. 45380 (CAS# 15086-94-9) is a photo-senseitive organic catalyst and has been used in the photocatalytic, diastereoselective additions of 1-sulfoximidoyl-1,2-benziodoxoles to styrenes, and in the stereoselective synthesis of 2-deoxyglycosides from glycals. Dyes and metabolites.

• synthetische

  Fluorescein (C.I. Acid Yellow 73, C.I. 45350) in water or ethanol solution bromide into four bromine derivatives, And made into a free acid form..

• Definition

  ChEBI: Bromoeosin is an organobromine compound. It is functionally related to a fluorescein (lactone form).

• Biologische Aktivität

  Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.

• Synthese

  

  2321-07-5

  

  15086-94-9

  The general procedure for the synthesis of 2',4',5',7'-tetrabromo-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthene]-3-one from 3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthene] is as follows: fluorescein in the form of the lactone (1 eq.), NaBr (16 eq.), and Oxone ( 6 equiv, 2KHSO5-KHSO4-K2SO4) were mixed and ground in an agate mortar until uniformly fine. The resulting solid mixture was reacted in an oven at 200 °C for 12 h. Upon completion of the reaction, the target product tetrabromofluorescein (4Br-F) was obtained in near 100% yield in the commercial disodium salt form known as eosin Y. The reaction mixture was diluted with water and the product was extracted with ethyl acetate. The product was characterized by mass spectrometry (ESI-MS) and spectroscopic techniques (1H-NMR and 13C-NMR). The specific data were as follows: ESI-MS (+) of 4Br-F: m/z 670.4 [M + H]+; 1H NMR (CH3OD): δ 7.04 ppm (s, 1H and 8H), 7.23 (d, J = 8.0 Hz, 3H), 7.72 (ddd, J = 8.0, 8.0, 1.2 Hz, 5H), 7.79 (ddd, J = 8.0, 8.0, 1.2 Hz, 4H), 8.09 ppm (d, J = 8.0 Hz, 6H).

• Properties and Applications

  brilliant yellow red. Soluble in water and ethanol for blue light red, with yellow green fluorescence. In concentrated sulfuric acid to yellow, dilution after yellow red precipitation.

• Einzelnachweise

  [1] Patent: US2008/61289, 2008, A1. Location in patent: Page/Page column 6-7
  [2] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 5, p. 216
  [3] Journal of the American Chemical Society, 1927, vol. 49, p. 1278
  [4] Justus Liebigs Annalen der Chemie, 1876, vol. 183, p. 31
  [5] Justus Liebigs Annalen der Chemie, 1910, vol. 372, p. 109

Solvent Red 43 Upstream-Materialien And Downstream Produkte

2-(3,6-Dihydroxy-2,4,5,7-tetrabromxanthen-9-yl)-benzoesure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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