Methylformiat

Bezeichnung:Methylformiat

CAS-Nr107-31-3

Englisch Name:Methyl formate

CBNumberCB9106448

SummenformelC2H4O2

Molgewicht60.05

MOL-Datei107-31-3.mol

Synonyma

Methylformiat

Ameisens?uremethylester

Methylmethanoat

Methylformiat physikalisch-chemischer Eigenschaften

Schmelzpunkt	-100 °C (lit.)
Siedepunkt	32-34 °C (lit.)
Dichte	0.974 g/mL at 20 °C (lit.)
Dampfdichte	2.1 (vs air)
Dampfdruck	32.91 psi ( 55 °C)
Brechungsindex	n20/D 1.343(lit.)
Flammpunkt	−16 °F
storage temp.	Store below +30°C.
Löslichkeit	300g/l, 25% soluble in water, miscible with alcohol, Propylene glycol, Glycerin and oils.
Aggregatzustand	Liquid
Farbe	Clear colorless
PH	4-5 (200g/l, H2O, 20℃)
Geruch (Odor)	Pleasant; agreeable.
Explosionsgrenze	5-23%(V)
Odor Threshold	130ppm
Geruchsart	fruity
Wasserlöslichkeit	300 G/L (20 ºC)
maximale Wellenlänge (λmax)	λ: 259 nm Amax: 1.00 λ: 260 nm Amax: 0.70 λ: 265 nm Amax: 0.20 λ: 270 nm Amax: 0.04 λ: 310-400 nm Amax: 0.01
Merck	14,6077
BRN	1734623
Henry's Law Constant	0.90 at 5.00 °C, 1.18 at 10.00 °C, 1.51 at 15.00 °C, 1.91 at 20.00 °C, 2.36 at 25.00 °C (column stripping-UV, Kutsuna et al., 2005)
Expositionsgrenzwerte	TLV-TWA 100 ppm (～250 mg/m³) (ACGIH, MSHA, and OSHA); TLV-STEL 150 ppm (～375 mg/m³) (ACGIH); IDLH 5000 ppm (NIOSH).
Dielectric constant	8.5（20℃）
Stabilität	Stable. Extremely flammable. Readily forms explosive mixtures with air. Note low flash point and very wide explosion limits. Incompatible with oxidizing agents.
LogP	-0.21 at 25℃
CAS Datenbank	107-31-3(CAS DataBase Reference)
NIST chemische Informationen	Methyl formate(107-31-3)
EPA chemische Informationen	Methyl formate (107-31-3)

Sicherheit

Kennzeichnung gefährlicher	F+,Xn
R-Sätze:	12-20/22-36/37
S-Sätze:	9-16-24-26-33
RIDADR	UN 1243 3/PG 1
OEB	A
OEL	TWA: 100 ppm (250 mg/m3), STEL: 150 ppm (375 mg/m3)
WGK Germany	1
RTECS-Nr.	LQ8925000
Selbstentzündungstemperatur	842 °F
TSCA	Yes
HS Code	2915 13 00
HazardClass	3
PackingGroup	I
Giftige Stoffe Daten	107-31-3(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rat > 4000 mg/kg
IDLA	4,500 ppm

Gefahreninformationscode (GHS)

Methyl formate Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die Dämpfe sind schwerer als Luft und können sich am Boden ausbreiten. Fernzündung möglich. Die Dämpfe mischen sich leicht mit Luft. Bildung explosionsfähiger Gemische.
CHEMISCHE GEFAHREN
Reagiert heftig mit Oxidationsmitteln.
ARBEITSPLATZGRENZWERTE
TLV: 100 ppm (als TWA); 150 ppm (als STEL); (ACGIH 2005).
MAK: 50 ppm, 120 mg/m? Spitzenbegrenzung: überschreitungsfaktor II(4); Hautresorption; Schwangerschaft: Gruppe C; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation der Dämpfe und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C kann sehr schnell eine gesundheitsschädliche Kontamination der Luft eintreten.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen und die Haut. Der Dampf reizt die Augen und die Atemwege. Möglich sind Auswirkungen auf das Zentralnervensystem. ärztliche Beobachtung notwendig.
LECKAGE
Gefahrenbereich verlassen! Ausgelaufene Flüssigkeit in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Kanalisation spülen. Persönliche Schutzausrüstung: Umgebungsluftunabhängiges Atemschutzgerät.
R-Sätze Betriebsanweisung:
R12:Hochentzündlich.
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
R36/37:Reizt die Augen und die Atmungsorgane.
S-Sätze Betriebsanweisung:
S9:Behälter an einem gut gelüfteten Ort aufbewahren.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S24:Berührung mit der Haut vermeiden.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S33:Maßnahmen gegen elektrostatische Aufladungen treffen.
Aussehen Eigenschaften
HCOOCH3; charakteristisch riechende, farblose Flüssigkeit.
Gefahren für Mensch und Umwelt
Hochentzündlich. Vorsicht: Siedepunkt (32^oC) liegt im Bereich möglicher Raumtemperaturen! Dämpfe bilden explosive Gemische mit Luft. Die schweren Dämpfe können eine beträchtliche Entfernung zu einer Zündquelle überbrücken. Heftige Reaktionen mit Oxidationsmitteln möglich.
Die Einatmung des Dampfes wirkt narkotisch, zugleich auch reizend auf die Schleimhäute des Respirationstraktes. Die mitunter verzögert einsetzenden Symptome sind Brennen der Augen, der Nasen- und Rachenschleimhäute und der Haut. Größere Dosen können bei längerer Einwirkung Leber- und Nierenschäden sowie Lungenödem hervorrufen. Bei wiederholtem Hautkontakt tereten häufig Dermatiden auf.
Schutzmaßnahmen und Verhaltensregeln
Verwendung nur unter dem Abzug. An gut gelüftetem Ort aufbewahren. Von Zündquellen fernhalten - Nicht rauchen.
Neopen-Handschuhe (nur kurzfristiger Spritzschutz!).
Vorbeugender Hautschutz durch Hautschutzsalbe.
Verhalten im Gefahrfall
Bei Verschütten: Kleine Spritzer verdampfen lassen, größere Mengen mit flüssigkeitsbindendem Material (z.B. Sand, Kieselgur, Universalbinder) aufnehmen und der Entsorgung zuführen.
Wassernebel, Schaum, Kohlendioxid, Löschpulver.
Erste Hilfe
Nach Hautkontakt: Mit Wasser und Seife abwaschen.
Nach Augenkontakt: Bei geöffnetem Lidspalt mit viel Wasser mindestens 10 Minuten spülen spülen. Augenarzt aufsuchen.
Nach Einatmen: Verletzten an die frische Luft bringen. Arzt aufsuchen.
Nach Verschlucken: Bei Verschlucken Wasser trinken lassen. Kein Erbrechen einleiten.
Nach Kleidungskontakt: Benetzte Kleidung ausziehen.
Ersthelfer: siehe gesonderten Anschlag
Sachgerechte Entsorgung
Abfallbehälter für halogenfreie organische Lösungsmittel
Beschreibung
Methyl Formate, also known as methyl methanoate, is the methyl ester of formic acid. The simplest example of an ester, it is a clear liquid with an ethereal odour, high vapor pressure, and low surface tension. It is an aromatic compound found in apples (Neubeller and Buchloh, 1986), and was identified as a volatile constituent in brewed, roasted, and dried coffee (Lovell et al., 1980); Methyl formate is used primarily to manufacture formamide, dimethylformamide, and formic acid. It is also used as a solvent for quick-drying finishes such as lacquers and in organic synthesis.
Chemische Eigenschaften
Methyl formate is a colorless liquid with a pleasant odor. Its solubility in water is 230 g/l at 25 °C (Riddick et al., 1985), but it reacts slowly with water to form formic acid and methyl alcohol (DOT, 1984). It is soluble in ether, chloroform, and is miscible with ethanol (Lide, 2000).
Physikalische Eigenschaften
Clear, colorless, mobile liquid with a pleasant, etheral odor. An odor threshold concentration of 130 ppm_v was reported by Nagata and Takeuchi (1990).
Verwenden
Methyl formate is used as a fumigant, as alarvicide for food crops, and as a solvent forcellulose acetate.
Verwenden
Methyl formate is used primarily to manufacture formamide, dimethyl formamide, and formic acid. Because of its high vapor pressure, it is used for quick - drying finishes. It is also used as an insecticide and to manufacture certain pharmaceuticals. Foam Supplies, Inc. has trademarked Ecomate, which is used as a blowing agent for foam insulation, as a replacement for CFC, HCFC, or HFCs, with zero ozone depletion potential and < 25 global warming potential.
A historical use of methyl formate, which sometimes brings it attention, was in refrigeration. Before the introduction of less-toxic refrigerants, methyl formate was used as an alternative to sulfur dioxide in domestic refrigerators, such as some models of the famous GE Monitor Top. Owners of methyl formate refrigerators should keep in mind that, even though they operate below atmospheric pressure, if evidence of a leak develops, they should take measures to avoid exposure to the ether-smelling liquid and vapor.
Vorbereitung Methode
In the laboratory, methyl formate can be produced by the condensation reaction of methanol and formic acid, as follows:
HCOOH + CH₃OH → HCOOCH₃ + H₂O
Industrial methyl formate, however, is usually produced by the combination of methanol and carbon monoxide (carbonylation) in the presence of a strong base, such as sodium methoxide :
CH₃OH + CO → HCOOCH₃
This process, practiced commercially by BASF among other companies gives 96 % selectivity toward methyl formate, although it can suffer from catalyst sensitivity to water, which can be present in the carbon monoxide feedstock, commonly derived from synthesis gas. Very dry carbon monoxide is, therefore, an essential requirement.
Definition
ChEBI: Methyl formate is a formate ester resulting from the formal condensation of formic acid with methanol. A low-boiling (31.5 ℃) colourless, flammable liquid, it has been used as a fumigant and larvicide for tobacco and food crops. It has a role as a polar aprotic solvent, a fumigant, an insecticide and a refrigerant. It is a formate ester, a methyl ester and a volatile organic compound. It is functionally related to a methanol.
Allgemeine Beschreibung
A clear colorless liquid with an agreeable odor. Flash point -27°F. Less dense than water Vapors heavier than air.
Air & Water Reaktionen
Highly flammable. Water soluble. Reacts slowly with water to give formic acid, a corrosive material, and methanol, a flammable liquid. Both products are dissolved in the water.
Reaktivität anzeigen
Methyl formate reacts with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated with caustic solutions. Flammable hydrogen is generated by mixing with alkali metals and hydrides.
Hazard
Flammable, dangerous fire and explosionrisk, explosive limits in air 5.9–20%. Eye, upperand lower respiratory tract irritant.
Health Hazard
Inhalation causes irritation of mucous membranes. Prolonged inhalation can produce narcosis and central nervous symptoms, including some temporary visual disturbance. Contact with liquid irritates eyes and may irritate skin if allowed to remain. Ingestion causes irritation of mouth and stomach and central nervous system depression, including visual disturbances.
Health Hazard
Methyl formate is a moderately toxic com pound affecting eyes, respiratory tract, andcentral nervous system. It is an irritant tothe eyes, nose, and lungs. Exposure to highconcentrations of its vapors in air may pro duce visual disturbances, irritations, narcoticeffects, and respiratory distress in humans.Such effects may be manifested at a 1-hourexposure to about 10,000-ppm concentration.Cats died of pulmonary edema from 2-hourexposure to this concentration
The acute oral toxicity of methyl formatewas low in test subjects. The symptoms werenarcosis, visual disturbances, and dyspnea.An oral LD50 value in rabbit is in the range1600 mg/kg..
Brandgefahr
Behavior in Fire: Vapor is heavier than air and may travel considerable distance to a source of ignition and flash back.
Sicherheitsprofil
Moderately toxic by ingestion. Inhalation of vapor can cause irritation to nasal passages and conjunctiva, optic neuritis, narcosis, retching, and death from pulmonary irritation. Industrial fatalities have occurred only with exposure to high concentrations. Flammable liquid. Very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. Explosive in the form of vapor when exposed to heat or flame. Reacts with methanol + sodium methoxide to form an explosive product. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.
mögliche Exposition
Methyl formate is used as a solvent; as an intermediate in pharmaceutical manufacture; and as a fumigant
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifing upper and lower lids. Seek med-facility. When this chemical has been swallowed, get medi-cal attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24- -48 h afterbreathing overexposure， as pulmonaryedema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a cortico-steroid spray.
Environmental Fate
Photolytic. Methyl formate, formed from the irradiation of dimethyl ether in the presence of chlorine, degraded to carbon dioxide, water, and small amounts of formic acid. Continued irradiation degraded formic acid to carbon dioxide, water, and hydrogen chloride (Kallos and Tou, 1977; Good et al., 1999).
A rate constant of 2.27 x 10^-12 cm³/molecule?sec was reported for the reaction of methyl formate and OH radicals in the atmosphere (Atkinson, 1989).
Chemical/Physical. Hydrolyzes slowly in water forming methanol and formic acid (NIOSH, 1997). Hydrolysis half-lives reported at 25 °C: 0.91 h at pH 9, 9.1 h at pH 8, 2.19 d at pH 7, and 21.9 d at pH 6 (Mabey and Mill, 1978).
Lager
Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.Prior to working with this chemical you should be trainedon its proper handling and storage. Before entering confinedspace where this chemical may be present, check to makesure that an explosive concentration does not exist. Methylformate must be stored to avoid contact with strong oxidizers, such as chlorine, bromine, chlorine dioxide, nitrates,and permanganates, since violent reactions occur. Store intightly closed containers in a cool, well-ventilated areaaway from heat. Sources of ignition, such as smoking andopen flames, are prohibited where methyl formate is handled, used, or stored. Metal containers involving the transferof 5 gallons or more of methyl formate should be groundedand bonded. Drums must be equipped with self-closingvalves, pressure vacuum bungs, and flame arresters. Useonly nonsparking tools and equipment, especially whenopening and closing containers of methyl formate.Wherever methyl formate is used, handled, manufactured,or stored, use explosion-proof electrical equipment andfittings.
Versand/Shipping
This compound requires a shipping label of“FLAMMABLE LIQUID.” It falls in Hazard Class 3 andPacking Group I.
läuterung methode
Wash the formate with strong aqueous Na2CO3, dry it with solid Na2CO3 and distil it from P2O5. (Procedure removes free alcohol or acid.) [Beilstein 2 IV 20.]
Inkompatibilitäten
May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Reacts slowly with water to form methanol and formic acid. Contact with water, steam releases formic acid. Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic, and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur)
Waste disposal
Incineration; atomizing in a suitable combustion chamber.
Einzelnachweise
Lee, Jae S., J. C. Kim, and Y. G. Kim. "Methyl formate as a new building block in C1 chemistry." Applied Catalysis 57.1 (1990): 1-30.
Handa, Yash Paul, et al. "Insulating Thermoplastic Foams Made With Methyl Formate-Based Blowing Agents." (2006).

Methyl formate Upstream-Materialien And Downstream Produkte

Methylformiat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

107-31-3, Methyl formate Verwandte Suche:

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