3-(3,5-Dichlorphenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexan-2,4-dion

Bezeichnung:3-(3,5-Dichlorphenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexan-2,4-dion

CAS-Nr32809-16-8

Englisch Name:Procymidone

CBNumberCB5447264

SummenformelC13H11Cl2NO2

Molgewicht284.14

MOL-Datei32809-16-8.mol

Synonyma

3-(3,5-Dichlorphenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexan-2,4-dion

3-(3,5-Dichlorphenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexan-2,4-dion physikalisch-chemischer Eigenschaften

Schmelzpunkt	166-167°C
Siedepunkt	477.9±35.0 °C(Predicted)
Dichte	d25 1.42-1.46
Dampfdruck	1.8 x 10^-2 Pa (25 °C)
Brechungsindex	1.6100 (estimate)
Flammpunkt	>100 °C
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Ethyl Acetate (Slightly)
Wasserlöslichkeit	4.5 mg l^-1 (25 °C)
pka	-2.67±0.60(Predicted)
Farbe	Off-White to Pale Beige
BRN	1539058
InChIKey	QXJKBPAVAHBARF-UHFFFAOYSA-N
CAS Datenbank	32809-16-8(CAS DataBase Reference)
NIST chemische Informationen	3-Azabicyclo[3.1.0]hexane-2,4-dione, 3-(3,5-dichlorophenyl)-1,5-dimethyl-(32809-16-8)
EPA chemische Informationen	Procymidone (32809-16-8)

Sicherheit

WGK Germany	2
RTECS-Nr.	GZ2150000
HS Code	29251900
Toxizität	LD50 in male rats (mg/kg): 6800 orally, >10000 dermally (Jackson); LD50 in male, female rats (g/kg): 7.8, 9.1 orally (Mikami)

Gefahreninformationscode (GHS)

Bildanzeige (GHS)
Alarmwort

Achtung
Gefahrenhinweise

H332：Gesundheitsschädlich bei Einatmen.

H360：Kann die Fruchtbarkeit beeinträchtigen oder das Kind im Mutterleib schädigen.

H370：Schädigt die Organe.

H373：Kann die Organe schädigen bei längerer oder wiederholter Exposition.

H411：Giftig für Wasserorganismen, mit langfristiger Wirkung.

H413：Kann für Wasserorganismen schädlich sein, mit langfristiger Wirkung.
Sicherheit

P260：Dampf/Aerosol/Nebel nicht einatmen.

P261：Einatmen von Staub vermeiden.

P264：Nach Gebrauch gründlich waschen.

P264：Nach Gebrauch gründlich waschen.

P270：Bei Gebrauch nicht essen, trinken oder rauchen.

P271：Nur im Freien oder in gut belüfteten Räumen verwenden.

P304+P340：BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.

P307+P311：BEI Exposition: GIFTINFORMATIONSZENTRUM oder Arzt anrufen.

P312：Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

P314：Bei Unwohlsein ärztlichen Rat einholen / ärztliche Hilfe hinzuziehen.

P321：Besondere Behandlung

P405：Unter Verschluss aufbewahren.

P501：Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Procymidone Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden
Systemic agricultural fungicide.
Verwenden
Procymidone is a systemic fungcide with both protective and curative activities used to control plant diseases such as fruit rots, grey mould on top fruits, vines and vegetables, and Sclerotinia rot of kidney beans and vegetable crops.
Definition
ChEBI: An azabicycloalkane that is 1,5-dimethyl-3-azabicyclo[3.1.0]hexane-2,4-dione in which the amino hydrogen is replaced by a 3,5-dichlorophenyl group. A fungicide widely used in horticulture as a seed dressing, pre-harvest spray or post-harvest dip for the co trol of various diseases.
Stoffwechselwegen
The fungicides, chlozolinate, vinclozolin, and procymidone, are added to wine after fermentation and the degradation products are isolated and identified. Chlozolinate undergoes a rapid hydrolytic loss of the ethoxycarbonyl substituent to give an oxazolidine that further undergoes hydrolytic cleavage to give 3' ,5' -dichloro-2-hydroxypropanilide. The oxazolidine ring of vinclozolin undergoes a similar hydrolysis reaction to give the corresponding anilide, 3' ,5'-dichloro-2-hydroxy-2-methylbut-3-eneanilide. Both of these anilides are stable in wine for 150 days. A different degradation behavior is observed with procymidone and leads to the formation of 3,5- dichloroaniline, which, in turn, breaks down in wine.
Degradation
Procymidone (1) was stable in acidic conditions (pH 2) but hydrolysed rapidly in buffer solutions (pH 6 to 10) and in natural river and sea water at 15, 30 and 45 °C with DTm values from 30 min to 8 days. Degradation occurred mainly via cleavage of the cyclic imide linkage in alkaline conditions and via cleavage of the subsequent amide linkage in acidic conditions (Mikami and Miyamoto, 1981) to yield the intermediate acid [2-( 3,5-dichlorophenylcarbamoyl)- 1,2 -dimet hylcyclopropanecarboxylic acid (2) and 1,2-dimethylcyclopropane-1,2-dicarboxylica cid (3) and 3,5- dichloroaniline (4) as terminal products (Villedieu et al., 1994,1995). Pirisi et al. (1986) and Cabras et al. (1984) reported the formation of compound 4 and other polar decomposition products in wine during the fermentation process.
Photodegradation of procymidone was investigated in various solutions after exposure to sunlight. Major degradation pathways were cleavage of the cyclic imide and the subsequent cleavage of the amide linkage to yield compounds 3 and 4 (Mikami and Miyamoto, 1981).

Procymidone Upstream-Materialien And Downstream Produkte

3-(3,5-Dichlorphenyl)-1,5-dimethyl-3-azabicyclo[3.1.0]hexan-2,4-dion Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

32809-16-8, Procymidone Verwandte Suche:

Send Inquriy