CARBOXYMETHYLCELLULOSE CALCIUM

Bezeichnung:CARBOXYMETHYLCELLULOSE CALCIUM

CAS-Nr9050-04-8

Englisch Name:CARBOXYMETHYLCELLULOSE CALCIUM

CBNumberCB8500399

SummenformelC23H30ClN3O

Molgewicht399.9568

MOL-Datei9050-04-8.mol

CARBOXYMETHYLCELLULOSE CALCIUM physikalisch-chemischer Eigenschaften

Löslichkeit	Practically insoluble in acetone, chloroform, ethanol (95%), toluene, and ether. Insoluble in water, but swells to form a suspension.
EPA chemische Informationen	Cellulose, carboxymethyl ether, calcium salt (9050-04-8)

Sicherheit

HS Code

3912310000

CARBOXYMETHYLCELLULOSE CALCIUM Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Carboxymethylcellulose calcium occurs as a white to yellowishwhite, hygroscopic, odorless powder.
Chemische Eigenschaften
DS 0.5-0.7
Verwenden
Pharmaceutic aid (tablet disintegrant).
Vorbereitung Methode
Cellulose, obtained from wood pulp or cotton fibers, is carboxymethylated, followed by conversion to the calcium salt. It is then graded on the basis of its degree of carboxymethylation and pulverized.
Pharmazeutische Anwendungen
The main use of carboxymethylcellulose calcium is in tablet formulations, where it is used as a binder, diluent, and disintegrant. Although carboxymethylcellulose calcium is insoluble in water, it is an effective tablet disintegrant as it swells to several times its original bulk on contact with water. Concentrations up to 15% w/w may be used in tablet formulations; above this concentration, tablet hardness is reduced.
Carboxymethylcellulose calcium is also used in other applications similarly to carboxymethylcellulose sodium; for example, as a suspending or viscosity-increasing agent in oral and topical pharmaceutical formulations. Carboxymethylcellulose calcium is also used in modern wound dressings for its water absorption, retention and hemostatic properties.
Sicherheit(Safety)
Carboxymethylcellulose calcium is used in oral and topical pharmaceutical formulations, similarly to carboxymethylcellulose sodium, and is generally regarded as a nontoxic and nonirritant material. However, as with other cellulose derivatives, oral consumption of large amounts of carboxymethylcellulose calcium may have a laxative effect.
Lager
Carboxymethylcellulose calcium is a stable, though hygroscopic material. It should be stored in a well-closed container in a cool, dry place.
Regulatory Status
Included in the FDA Inactive Ingredients Database (oral, capsules and tablets). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

CARBOXYMETHYLCELLULOSE CALCIUM Upstream-Materialien And Downstream Produkte

CARBOXYMETHYLCELLULOSE CALCIUM Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

9050-04-8, CARBOXYMETHYLCELLULOSE CALCIUM Verwandte Suche:

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