Benzylisocyanid

Bezeichnung:Benzylisocyanid

CAS-Nr10340-91-7

Englisch Name:Benzyl isocyanide

CBNumberCB8765835

SummenformelC8H7N

Molgewicht117.15

MOL-Datei10340-91-7.mol

Synonyma

Benzylisocyanid

Benzylisocyanid physikalisch-chemischer Eigenschaften

Siedepunkt	105-106 °C75 mm Hg(lit.)
Dichte	0.962 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.521(lit.)
Flammpunkt	175 °F
storage temp.	-20°C
pka	27.4
Aggregatzustand	clear liquid
Farbe	Colorless to Red to Green

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/21/22
S-Sätze:	36/37
RIDADR	UN 3334
WGK Germany	3
HS Code	29269090

Gefahreninformationscode (GHS)

Benzyl isocyanide Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
clear colorless to yellowish liquid
Verwenden
Benzyl Isocyanide is used in the preparation of arylamide compounds. also used as a catalyst in the cycloaddition of norbornenes with internal and terminal acetylenes.
Application
Benzyl isocyanide forms phosphaalkene-containing complexes. Benzyl isocyanide was used in the synthesis of Ru(II) complexes containing hydrazine and benzyl isocyanide ligands. It was used in a three-component coupling process leading to O- and N-arylamides.
Synthese
Synthesis of benzyl isocyanide
In a 500-mL, round-bottomed flask equipped with a magnetic stirring bar and a pressure-equalizing funnel are placed 5-benzylaminotetrazole (10.5 g, 60 mmol), 100 mL of 10% sodium hydroxide solution, and 70 mL of dichloromethane. The mixture is cooled to 0°C and a solution of NaOBr in water (165 mL, 65 mmol) (Note 2) is added with vigorous stirring over a 15-min period (Note 3). The dichloromethane layer is separated and the aqueous phase extracted with five 50-mL portions of dichloromethane. The combined dichloromethane extracts are dried over anhydrous MgSO4, the drying agent is removed by filtration, and the dichloromethane is removed by simple distillation. The pressure is then reduced to ~20 mm with an aspirator and benzyl isocyanide is distilled at 98–100°C; yield: 5.91 g (84%) (Note 4) and (Note 5).
Organic Syntheses, Coll. Vol. 7, p. 27, 1990
http://www.orgsyn.org

Benzylisocyanid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

10340-91-7, Benzyl isocyanide Verwandte Suche:

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