N,N,N',N'-Tetramethylacridin-3,6-diaminmonohydrochlorid, Verbindung mit Zinkdichlorid

Bezeichnung:N,N,N',N'-Tetramethylacridin-3,6-diaminmonohydrochlorid, Verbindung mit Zinkdichlorid

CAS-Nr10127-02-3

Englisch Name:Basic Orange 14

CBNumberCB7378881

SummenformelC17H20Cl3N3Zn

Molgewicht438.1

MOL-Datei10127-02-3.mol

Synonyma

N,N,N',N'-Tetramethylacridin-3,6-diaminmonohydrochlorid, Verbindung mit Zinkdichlorid

N,N,N',N'-Tetramethylacridin-3,6-diaminmonohydrochlorid, Verbindung mit Zinkdichlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	165 °C
storage temp.	room temp
Löslichkeit	H2O: soluble1mg/mL, clear, orange to very deep orange
Colour Index	46005
Aggregatzustand	Solid
pka	pKa -3.3(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);0.2(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);10.1(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain)
Farbe	Red brown
PH	3.9 (10g/l, H2O, 20℃)
Wasserlöslichkeit	soluble
Sensitive	Hygroscopic
BRN	3734978
Stabilität	Stable. Incompatible with strong oxidizing agents. Protect from moisture. Hygroscopic.
CAS Datenbank	10127-02-3(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	68-20/21/22-36/37/38
S-Sätze:	45-36/37-36-26
WGK Germany	3
RTECS-Nr.	AR7600000
HS Code	32041300
Toxizität	A dye used to stain nucleic acids. It fluoresces at 530 nm when intercalated into double stranded DNA, or at 640 nm when ionically bound to single stranded DNA. It produces mutations, some involving reading frame shifts, other deletions or insertions and is carcinogenic. It is also known to be a dermal phototoxicant.

Gefahreninformationscode (GHS)

Basic Orange 14 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R68:Irreversibler Schaden möglich.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
brown powder
Verwenden
Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.
Verwenden
Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.
Allgemeine Beschreibung
Acridine orange is a metachromatic fluorescent cationic dye that permeates the cell membrane and intercalates DNA and RNA. It allows for visual detection of nucleic acids on agarose and polyacrylamide gels.
Biochem/physiol Actions
Acridine orange (AO) is a fluorescent dye with two different staining characteristics. In fixed tissues, it acts as a metachromatic dye and differentially stains DNA (green) and RNA (orange). But, in living cells it acts as a pH indicator and produce brilliant orange-red in acidic condition. AO has been used to identify apoptotic cells in drosophila embryos. Acridine Orange staining method has been used to deliver more consistent data in the micronucleus test.

Basic Orange 14 Upstream-Materialien And Downstream Produkte

N,N,N',N'-Tetramethylacridin-3,6-diaminmonohydrochlorid, Verbindung mit Zinkdichlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

10127-02-3, Basic Orange 14 Verwandte Suche:

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