4-(1,1,3,3-Tetramethylbutyl)phenol

Bezeichnung:4-(1,1,3,3-Tetramethylbutyl)phenol

CAS-Nr140-66-9

Englisch Name:4-tert-Octylphenol

CBNumberCB6724049

SummenformelC14H22O

Molgewicht206.32

MOL-Datei140-66-9.mol

Synonyma

4-(1,1,3,3-Tetramethylbutyl)phenol

4-(1,1,3,3-Tetramethylbutyl)phenol physikalisch-chemischer Eigenschaften

Schmelzpunkt	79-82 °C(lit.)
Siedepunkt	175 °C30 mm Hg(lit.)
Dichte	0.95 g/cm3 (20℃)
Dampfdruck	2Pa at 38℃
Brechungsindex	1.5003 (estimate)
Flammpunkt	145 °C
storage temp.	-20°C
Löslichkeit	water: slightly soluble0.007g/L at 20°C
pka	10.15±0.15(Predicted)
Aggregatzustand	Solid
Farbe	White flakes
Säure-Base-Indikators(pH-Indikatoren)	6 at 10 g/l at 20 °C
Wasserlöslichkeit	7mg/L at 20℃
BRN	513992
Stabilität	Stable. Incompatible with strong oxidizing agents, strong bases.
LogP	4.8 at 22℃
CAS Datenbank	140-66-9(CAS DataBase Reference)
NIST chemische Informationen	Phenol, 4-(1,1,3,3-tetramethylbutyl)-(140-66-9)
EPA chemische Informationen	p-(1,1,3,3-Tetramethylbutyl)phenol (140-66-9)

Sicherheit

Kennzeichnung gefährlicher	Xn,N,Xi,F
R-Sätze:	21-38-41-50/53-67-66-36-11-52/53-68-62-40
S-Sätze:	26-36-61-60-39-16-9
RIDADR	2430
WGK Germany	2
RTECS-Nr.	SM9625000
HazardClass	8
PackingGroup	III
HS Code	29071300
Giftige Stoffe Daten	140-66-9(Hazardous Substances Data)

Gefahreninformationscode (GHS)

4-tert-Octylphenol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R21:Gesundheitsschädlich bei Berührung mit der Haut.
R38:Reizt die Haut.
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white powder
Verwenden
4-tert-Octylphenol (4t-OP) is used in manufacturing processes as an intermediate in the generation of surfactants, synthetic rubber additives, or resins. 4t-OP is also used to manufacture alkylphenol ethoxylates. It is found mainly in detergents, cleaning products, and emulsifiers and less frequently in paints, personal care products, pesticides, paper, pulp, and textiles.
Definition
ChEBI: 4-tert-Octylphenol is an alkylbenzene.
Allgemeine Beschreibung
4-tert-Octylphenol is a potential environmental pollutant and it exhibits toxic and estrogenic effects on mammalian cells. It binds to estrogen receptors and exerts estrogenic actions in vitro. The transformation of the 4-tert-octylphenol upon irradiation at 253.7nm and by hydroxyl radicals generated by the photolysis (λ_exc = 253.7nm) of hydrogen peroxide in aqueous solution has been studied.
Auswirkungen auf die Gesundheit
4-tert-octylphenol (OP) is an endocrine-disrupting chemical that causes harmful effects to human health.a common environmental pollutant showing weak estrogenic effects. 4-tert-Octylphenol has been shown to cause harm to the male reproductive system of vertebrates.
High doses of several alkylphenols, including 4- tert-octylphenol, have altered estrogenic effects, including sex hormone levels, estrus cycles, reproductive outcomes, neonatal sexual development, as well as impaired production of steroid hormone and testicular atrophy.
Environmental Fate
Studies have shown that 4t-OP will adsorb to sediments.
läuterung methode
Crystallise the phenol from n-hexane and/or distil it in a vacuum. [Beilstein 6 III 2051, 6 IV 3484.]
Toxicity evaluation
4t-OP has been shown to be an estrogen receptor (ER) agonist. Estrogenic effects of 4t-OP have been demonstrated in human cells, with 4t-OP displacing the natural estrogen 17b estradiol from its receptor, and 4t-OP inducing cell proliferation in estrogen-dependent cell proliferation assays. In vivo confirmation of 4t-OP’s estrogenicity has been confirmed with the uterotrophic assay.

4-tert-Octylphenol Upstream-Materialien And Downstream Produkte

4-(1,1,3,3-Tetramethylbutyl)phenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

140-66-9, 4-tert-Octylphenol Verwandte Suche:

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