Thiophen-2-thiol

Bezeichnung:Thiophen-2-thiol

CAS-Nr7774-74-5

Englisch Name:2-Thiophenethiol

CBNumberCB6257655

SummenformelC4H4S2

Molgewicht116.2

MOL-Datei7774-74-5.mol

Synonyma

Thiophen-2-thiol

Thiophen-2-thiol physikalisch-chemischer Eigenschaften

Siedepunkt	129 °C(lit.)
Dichte	1.252 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.62(lit.)
FEMA	3062 \| 2-THIENYL MERCAPTAN
Flammpunkt	150 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
Löslichkeit	soluble in Chloroform, DMSO
Aggregatzustand	clear liquid
pka	6.38±0.43(Predicted)
Farbe	Light yellow to Brown
Geruch (Odor)	at 0.10 % in dipropylene glycol. burnt caramel roasted coffee
Geruchsart	caramellic
Sensitive	Air Sensitive
JECFA Number	1052
BRN	104650
InChIKey	SWEDAZLCYJDAGW-UHFFFAOYSA-N
LogP	2.20
CAS Datenbank	7774-74-5(CAS DataBase Reference)
NIST chemische Informationen	2-Thiophenethiol(7774-74-5)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-36/38-21/22-20/22
S-Sätze:	26-36-36/37/39
RIDADR	UN3334
WGK Germany	3
F	10-13-23
Hazard Note	Irritant
HazardClass	9
PackingGroup	III
HS Code	29349990

Gefahreninformationscode (GHS)

2-Thiophenethiol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36/38:Reizt die Augen und die Haut.
R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
2-Thienyl mercaptan has a very unpleasant, burnt caramellic and sulfuraceous odor with a similar flavor.
Chemische Eigenschaften
Clear yellowish to orange liquid
Verwenden
2-Thiophenethiol is used in biological studies to evaluate the changes in key odorants of hazelnut induced by roasting.
Definition
ChEBI: Thiophene-2-thiol is a heteroarene.
synthetische
By heating sodium sulfosuccinate with phosphorous trichloride; also by reduction of thiophene-2-sulfonyl chloride.
Synthesis Reference(s)
Journal of the American Chemical Society, 75, p. 6316, 1953 DOI: 10.1021/ja01120a518
Synthese
A three-necked flask fitted with a mechanical stirrer and a 600-ml dropping funnel filled with dry nitrogen is charged with 500 ml of tetrahydrofuran and 56 g (53 ml, 0.67 mole) of thiophene. This mixture is stirred under nitrogen and cooled to ?40° with an acetone–dried ice bath while 490 ml (0.662 mole) of 1.35 M n-butyllithium in pentane is added over 5 minutes via the dropping funnel. The mixture's temperature is held between ?30° and ?20° for 1 hour, then lowered to ?70° by adding dry ice to the bath. Powdered sulfur crystals (20.4 g, 0.638 g) are added to the stirred mixture in one aliquot. After 30 minutes, the temperature is allowed to rise to ?10°, and then the yellow solution is carefully poured into 1 l of rapidly stirred ice water. These aqueous extracts are combined with the aqueous layer, and the whole is chilled and carefully acidified with 4 N sulfuric acid. This aqueous phase is immediately extracted with three 200-ml portions of diethyl ether. The combined ether extracts are washed twice with 100 ml portions of water to remove acid and remaining tetrahydrofuran and dried over anhydrous sodium sulfate. After the removal of ether, the residual golden-brown oil is purified by distillation at reduced pressure. The portion boiling at 53–56° (5 mm) is collected, yielding 49.5–53.5 g (65–70%) of 2-thiophenethiol as a yellow oil.

2-Thiophenethiol Upstream-Materialien And Downstream Produkte

Thiophen-2-thiol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7774-74-5, 2-Thiophenethiol Verwandte Suche:

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