4-Pyridoxic acid Struktur

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinsure

Bezeichnung:3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinsure

CAS-Nr82-82-6

Englisch Name:4-Pyridoxic acid

CBNumberCB6151957

SummenformelC8H9NO4

Molgewicht183.16

MOL-Datei82-82-6.mol

Synonyma

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinsure

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	258-261 °C (dec.) (lit.)
Siedepunkt	584.5±50.0 °C(Predicted)
Dichte	1.480±0.06 g/cm3(Predicted)
storage temp.	-20°C
Löslichkeit	Aqueous Base (Slightly), Water (Very Slightly)
Aggregatzustand	Solid
pka	0.47±0.25(Predicted)
Farbe	Pale Beige to Light Brown
Merck	13,8071
Stabilität	Hygroscopic

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	2
RTECS-Nr.	NS1800000

Gefahreninformationscode (GHS)

4-Pyridoxic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
4-Pyridoxic Acid, a catabolite of vitamin B6 (P991735), is a water-soluble B-group vitamin that can be used as a urinary diagnostic biomarker for determining the nutritional status of these vitamins.
Definition
ChEBI: 4-pyridoxic acid is a methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine. It has a role as a mouse metabolite and a human urinary metabolite. It is a member of methylpyridines, a hydroxymethylpyridine, a monohydroxypyridine and a vitamin B6. It is functionally related to an isonicotinic acid. It is a conjugate acid of a 4-pyridoxate.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 4, p. 625, 1967 DOI: 10.1002/jhet.5570040427
Enzyminhibitor
This oxidized derivative (FW = 171.15 g/mol) of pyridoxal is the chief catabolic product of pyridoxine, pyridoxal, and pyridoxamine degradation; it can be isolated from human urine. The carboxyl group has a pKa value of 5.50 while the phenolic OH has a value of 9.75. 4-Pyridoxic acid has a blue fluorescence which is maximal between pH 3 and 4. Heating 4-pyridoxic acid in 0.5 N acid will convert the metabolite to its lactone, which has an even stronger fluorescence. Target(s): dextransucrase; glucose dehydrogenase; pyridoxal dehydrogenase; and pyridoxaminephosphate oxidase.

4-Pyridoxic acid Upstream-Materialien And Downstream Produkte

3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

82-82-6, 4-Pyridoxic acid Verwandte Suche:

Send Inquriy