3-Fursaeure

Bezeichnung:3-Fursaeure

CAS-Nr488-93-7

Englisch Name:3-Furoic acid

CBNumberCB5473553

SummenformelC5H4O3

Molgewicht112.08

MOL-Datei488-93-7.mol

Synonyma

3-Fursaeure

3-Fursaeure physikalisch-chemischer Eigenschaften

Schmelzpunkt	120-122 °C (lit.)
Siedepunkt	229.64°C
Dichte	1.3220
Brechungsindex	1.4710 (estimate)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pka	3.9(at 25℃)
Farbe	Off-White to Beige
Wasserlöslichkeit	insoluble
BRN	108638
InChIKey	IHCCAYCGZOLTEU-UHFFFAOYSA-N
LogP	1.030
CAS Datenbank	488-93-7(CAS DataBase Reference)
NIST chemische Informationen	3-Furancarboxylic acid(488-93-7)

Sicherheit

Kennzeichnung gefährlicher	Xi,C
R-Sätze:	36/37/38-34
S-Sätze:	26-36/37-45-36/37/39-36
WGK Germany	3
HazardClass	IRRITANT
HS Code	29321900

Gefahreninformationscode (GHS)

3-Furoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
3-Furoic acid, also known as 3-carboxyfuran or 3-furoate, belongs to the class of organic compounds known as furoic acids. These are organic compounds containing a furoic acid moiety, with a structure characterized by a furan ring bearing a carboxylic acid group at the C2 or C3 carbon atom.
3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals. It is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
3-Furoic acid can be used as a reactant to synthesize:
- Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
- (±)-Hyperolactone A by reacting with 2-methylbutanal.
- Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.
Verwenden
3-Furoic acid can be used as a reactant to synthesize:
Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
(±)-Hyperolactone A by reacting with 2-methylbutanal.
Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.
Verwenden
3-Furoic acid is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Definition
ChEBI: A furoic acid carrying the carboxy group at position 3.
Synthesis Reference(s)
Tetrahedron Letters, 26, p. 1509, 1985 DOI: 10.1016/S0040-4039(00)98538-1
Biologische Aktivität
3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Biochem/physiol Actions
3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
läuterung methode
Crystallise the acid from water or aqueous EtOH, and sublime it in a vacuum. [Beilstein 18 I 439, 18 III/IV 4052, 18/6 V 196.]

3-Furoic acid Upstream-Materialien And Downstream Produkte

3-Fursaeure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

488-93-7, 3-Furoic acid Verwandte Suche:

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