6-Aminohexan-1-ol

Bezeichnung:6-Aminohexan-1-ol

CAS-Nr4048-33-3

Englisch Name:6-Amino-1-hexanol

CBNumberCB5104017

SummenformelC6H15NO

Molgewicht117.19

MOL-Datei4048-33-3.mol

Synonyma

6-Aminohexan-1-ol

6-Aminohexan-1-ol physikalisch-chemischer Eigenschaften

Schmelzpunkt	54-58 °C (lit.)
Siedepunkt	135-140 °C/30 mmHg (lit.)
Dichte	0.8872 (estimate)
Brechungsindex	1.4444 (estimate)
Flammpunkt	133 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	DMSO (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka	15.18±0.10(Predicted)
Aggregatzustand	Crystals
Farbe	Light yellow to brown
Wasserlöslichkeit	MISCIBLE
Sensitive	Hygroscopic
BRN	1732524
Stabilität	Hygroscopic. Stable. Incompatible with strong oxidizing agents.
InChIKey	SUTWPJHCRAITLU-UHFFFAOYSA-N
CAS Datenbank	4048-33-3(CAS DataBase Reference)
NIST chemische Informationen	NH2(CH2)6OH(4048-33-3)
EPA chemische Informationen	1-Hexanol, 6-amino- (4048-33-3)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-37/39-36
WGK Germany	3
RTECS-Nr.	MO8840000
F	3-10
HazardClass	IRRITANT, HYGROSCOPIC
HS Code	29221990

Gefahreninformationscode (GHS)

6-Amino-1-hexanol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
slightly yellow crystalline powder
Verwenden
6-Amino-1-hexanol can undergo cyclization over copper supported on γ-alumina and magnesia to form hexahydro-1H-azepine. It may be used along with glutaric acid to generate poly(ester amide)s with excellent film- and fiber forming properties.
Verwenden
6-Amino-1-hexanol is used as pharmaceutical intermediate.
Verwenden
6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiprolifer ative and antimigratory activity. Behery, F
Synthese
By volume ratio, 1 part of 6-aminohexanoic acid was added to the reactor containing 15 parts of diethyl ether or dry toluene solution At 40 ℃ constant temperature, At 1500rpm / min speed, rapidly injected 2 parts of a solution of sodium borohydride. At 250W, ultrasonic treatment 20min. Then, dropwise under reflux, 8 parts of ethylene glycol solution. Dropwise addition time was 30 minutes. Finally, at 90 ℃ and at a rate of 800rpm/min, maintain temperature under stirring and react for 16 h to obtain the reaction crude product. (2) By the amount of parts count, step (1) preparation of 1 part of the reaction crude was added 6 parts water for hydrolysis. Undrego vacuum distillation, collecting 125 ℃ fraction, to obtain the 6-amino-1-hexanol product.

6-Amino-1-hexanol Upstream-Materialien And Downstream Produkte

6-Aminohexan-1-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

4048-33-3, 6-Amino-1-hexanol Verwandte Suche:

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