Linolensure

Bezeichnung:Linolensure

CAS-Nr463-40-1

Englisch Name:Linolenic acid

CBNumberCB2112323

SummenformelC18H30O2

Molgewicht278.43

MOL-Datei463-40-1.mol

Synonyma

Linolensure

Linolensure physikalisch-chemischer Eigenschaften

Schmelzpunkt	-11 °C(lit.)
Siedepunkt	230-232 °C1 mm Hg(lit.)
Dichte	0.914 g/mL at 25 °C(lit.)
FEMA	3380 \| 9,12-OCTADECADIENOIC ACID (48%) AND 9,12,15-OCTADECATRIENOIC ACID (52%)
Brechungsindex	n20/D 1.480(lit.)
Flammpunkt	>230 °F
storage temp.	2-8°C
Löslichkeit	Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
Aggregatzustand	Liquid
pka	4.78±0.10(Predicted)
Farbe	Clear colorless to light yellow
Wichte	0.91
Geruch (Odor)	faint fatty
Wasserlöslichkeit	INSOLUBLE
Merck	14,5506
BRN	1727693
InChIKey	DTOSIQBPPRVQHS-PDBXOOCHSA-N
LogP	6.52
CAS Datenbank	463-40-1(CAS DataBase Reference)
NIST chemische Informationen	9,12,15-Octadecatrienoic acid, (Z,Z,Z)-(463-40-1)
EPA chemische Informationen	Linolenic acid (463-40-1)

Sicherheit

R-Sätze:	36/37/38
S-Sätze:	26-36-37/39
RIDADR	UN1170 - class 3 - PG 2 - Ethanol
WGK Germany	1
F	8-10-23
HS Code	29161500

Gefahreninformationscode (GHS)

Linolenic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Linolenic acid (LA), also known as Alpha-linolenic acid (ALA), is an omega-3 essential fatty acid with a wide range of biological activities such as cardiovascular protection, anticancer, neuroprotection, anti-osteoporosis, anti-inflammatory, and antioxidant.LA is mainly sourced from plants, such as nuts and seeds, and is used for the endogenous synthesis of LC omega-6 fatty acids. It is used medicinally as a nutritional supplement and to treat dietary deficiencies or imbalances.
Chemische Eigenschaften
clear light yellow to yellow liquid
Occurrence
linolenic acid occurs as the glyceride in many seed fats. It is an essential fatty acid in the diet.
Verwenden
linolenic acid is also known as alpha-linolenic acid; omega-3. An essential fatty acid found in most drying oils. It is slightly irritating to the mucous membranes. It may be used in a cosmetic preparation for any of the following broad uses: anti-static, cleansing, emollient, skin-conditioning, and surfactant properties.
Verwenden
Linolenic acid has been used:
- to assess the total antioxidative activity of serum and bacteria
- in palleroni chamber assay
- to prepare free fatty acid mixture
Verwenden
An essential fatty acid. Occurs as the glyceride in most drying oils. Nutrient.
Definition
ChEBI: Alpha-linolenic acid is a linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect. It has a role as a micronutrient, a nutraceutical and a mouse metabolite. It is an omega-3 fatty acid and a linolenic acid. It is a conjugate acid of an alpha-linolenate and a (9Z,12Z,15Z)-octadeca-9,12,15-trienoate.
Definition
linolenic acid: A liquid polyunsaturatedfatty acid with three doublebonds in its structure:CH₃CH₂CH:CHCH₂CH:CHCH₂CH:CH-(CH₂)₇COOH. It occurs in certainplant oils, e.g. linseed and soya-beanoil, and in algae. It is one of the essentialfatty acids.
benefits
Linolenic acid (LA) is an essential fatty acid with anti-inflammatory, anti-bacterial, anti-atherosclerotic and anti-cancer activities, and has a variety of health benefits, including: lowering high blood pressure and cholesterol, lowering the risk of heart disease, maintaining the membrane fluidity of the epidermal transdermal water barrier, improving the barrier function of the skin, decreasing inflammation, regulating sebum secretion, moisturising the scalp, promoting hair growth and prevents hair breakage. It also has a whitening effect on over-pigmented skin.
Allgemeine Beschreibung
Linolenic acid is a clear colorless liquid. (NTP, 1992)
Air & Water Reaktionen
Oxidizes in air to form peroxides, which spontaneously ignite. Insoluble in water. Sensitive to heat and moisture.
Reaktivität anzeigen
Linolenic acid is incompatible with bases, oxidizing agents and reducing agents. Also incompatible with peroxides, oxygen and water.
Brandgefahr
Linolenic acid is probably combustible.
Biochem/physiol Actions
An ω-3 fatty acid that serves as a precursor to eicosapentaenoic acid (EPA) but not docosahexaenoic acid. Conversion is greater in women than men, and conversely, β-oxidation metabolism is greater in men than women.
Carcinogenicity
Narisawa et al. found that diets high in perilla oil (with high a-linolenic acid but also high levels of linoleic acid) lowered the risk of colon cancer in a rat model initiated with the carcinogen N-methyl-Nnitrosourea. Okuno found a suppressive effect on diethylnitrosamine- induced heptaocarcinogenesis in male Fischer 344 rats treated with either safflower (high in linoleic acid) or perilla oil (high in both linoleic and α-linolenic acids). Kitano et al. found that 10% α-linolenic acid did not promote urninary bladder cancer initiated in rats with N-butyl-N-(4-hydrocybutyl)nitrosamine. Mice fed a-linolenic acid at 5–10% of the diet had increased mammary gland ductular cell proliferation.

Linolenic acid Upstream-Materialien And Downstream Produkte

Linolensure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

463-40-1, Linolenic acid Verwandte Suche:

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