(S)-(+)-1-Aminopropan-2-ol

Bezeichnung:(S)-(+)-1-Aminopropan-2-ol

CAS-Nr2799-17-9

Englisch Name:(S)-(+)-1-Amino-2-propanol

CBNumberCB1693195

SummenformelC3H9NO

Molgewicht75.11

MOL-Datei2799-17-9.mol

Synonyma

(S)-(+)-1-Aminopropan-2-ol

(S)-(+)-1-Aminopropan-2-ol physikalisch-chemischer Eigenschaften

Schmelzpunkt	24-26 °C(lit.)
alpha	18 º (c=1.8, H2O)
Siedepunkt	160 °C(lit.)
Dichte	0.954 g/mL at 25 °C(lit.)
Dampfdichte	2.6 (vs air)
Dampfdruck	<1 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.4437(lit.)
Flammpunkt	169 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Methanol (Sparingly), Water (Sparingly)
pka	12.92±0.35(Predicted)
Aggregatzustand	Liquid After Melting
Farbe	Clear colorless to pale yellow
Wichte	0.954
Optische Rotation	[α]20/D +18°, c = 1.8 in H2O
Wasserlöslichkeit	soluble
Sensitive	Hygroscopic
BRN	1718868
Erinnerung an die inhaltsstoffe	(S)-(+)-1-Amino-2-propanol (2799-17-9)
InChI	1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3/t3-/m0/s1
InChIKey	HXKKHQJGJAFBHI-VKHMYHEASA-N
SMILES	C[C@H](O)CN
LogP	-1.127 (est)
CAS Datenbank	2799-17-9(CAS DataBase Reference)
NIST chemische Informationen	2-Propanol, 1-amino-, (S)-(2799-17-9)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	34
S-Sätze:	23-26-36-45
RIDADR	UN 3259 8/PG 2
WGK Germany	1
RTECS-Nr.	UA5775000
F	10-34
HazardClass	8
PackingGroup	III
HS Code	29221980
Speicherklasse	8A - Combustible corrosive hazardous materials
Hazard Classifications	Skin Corr. 1B

Gefahreninformationscode (GHS)

(S)-(+)-1-Amino-2-propanol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
colorless to light yellow liquid
Verwenden
(S)-(+)-1-Amino-2-propanol may be used in the preparation of S-(+)-1-(2,3-naphthalimido)-2-propanol.
Verwenden
Emulsifying agent, drycleaning soaps, soluble textile oils, wax removers, metal-cutting oils, cosmetics, emulsion paints, plasticizers, insecticides.
Allgemeine Beschreibung
(S)-(+)-1-Amino-2-propanol is a chiral amino alcohol.
Synthese
Step (1): dissolve sodium tert-butoxide (230g, 2.39mol) in tetrahydrofuran (2L), slowly add trifluoroacetamide (226g, 2mol) under the ice bath, stirring for 30min; then add S-epoxypropane (128g, 2.2mol) under the ice bath, naturally warmed to room temperature, and continue to stir the reaction for 10h, and then stirred the reaction for another 2h at 35; after the reaction After the reaction, 2N (equivalent concentration) of hydrochloric acid was added dropwise to the system for neutralization, and then 1L of water was added, static layering, the aqueous phase was extracted with dichloromethane, the organic phases were combined, dried with anhydrous sodium sulfate, and concentrated under pressure to obtain a total of 318g of intermediate product I, with a yield of 93%. Step (2): dissolve the intermediate product I (310g, 1 .81mol) obtained in step (1) in methanol (1 .5L), add 200mL of water and potassium carbonate (550g, 4mol), stirring at room temperature for 6h, filtration, concentration to dryness, the product obtained was dissolved in dichloromethane, filtration, insoluble matter was removed, anhydrous sodium sulfate was dried, concentration, distillation under reduced pressure, the target product S 1-amino-2-propanol totaling 122 g in 90% yield.

(S)-(+)-1-Amino-2-propanol Upstream-Materialien And Downstream Produkte

(S)-(+)-1-Aminopropan-2-ol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2799-17-9, (S)-(+)-1-Amino-2-propanol Verwandte Suche:

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