Ginsenoside Rg2

Bezeichnung:Ginsenoside Rg2

CAS-Nr52286-74-5

Englisch Name:Ginsenoside Rg2

CBNumberCB1483174

SummenformelC42H72O13

Molgewicht785.03

MOL-Datei52286-74-5.mol

Ginsenoside Rg2 physikalisch-chemischer Eigenschaften

Schmelzpunkt	187～189℃
Siedepunkt	881.0±65.0 °C(Predicted)
Dichte	1.30±0.1 g/cm3(Predicted)
storage temp.	2-8°C
Löslichkeit	Methanol (Slightly, Heated, Sonicated), Pyridine (Slightly, Sonicated)
pka	12.85±0.70(Predicted)
Aggregatzustand	Solid
Farbe	White to Off-White
Stabilität	Hygroscopic
InChIKey	AGBCLJAHARWNLA-DJZXLMSJSA-N
LogP	6.830 (est)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
S-Sätze:	24/25
WGK Germany	3
RTECS-Nr.	LZ6430000
HS Code	29389090
Toxizität	mouse,LD50,intraperitoneal,1340mg/kg (1340mg/kg),Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 343, 1975.

Gefahreninformationscode (GHS)

Ginsenoside Rg2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Ginsenosides are pharmacologically active natural compounds from ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rg₂ is a protopanaxatriol that is more abundant in some Panax species (e.g., white and red P. ginseng) than others. This ginsenoside and its metabolites have diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-diabetic actions. It also protects against DNA damage and apoptosis induced by ultraviolet light. Notably, this ginsenoside is increased by the metabolism of other bioactive ginsenosides during the steaming or heating of plant materials, particularly in P. quinquefolium.
Chemische Eigenschaften
White solid
Verwenden
20(S)-Ginsenoside Rg2 is used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory activity. It exists as a bioactive metabolite of the ginsenoside component of Panax ginseng.
Definition
ChEBI: Ginsenoside Rg2 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, a cardioprotective agent and an anticoagulant. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a ginsenoside, a tetracyclic triterpenoid, a disaccharide derivative, a 20-hydroxy steroid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Ginsenoside Rg2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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