20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid

Bezeichnung:20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid

CAS-Nr11021-13-9

Englisch Name:GINSENOSIDE RB2

CBNumberCB3666050

SummenformelC53H90O22

Molgewicht1079.27

MOL-Datei11021-13-9.mol

Synonyma

20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid

20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid physikalisch-chemischer Eigenschaften

Schmelzpunkt	197～199℃
Siedepunkt	1117.1±65.0 °C(Predicted)
Dichte	1.42±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,2-8°C
Löslichkeit	DMSO (Slightly), Methanol (Slightly, Sonicated)
pka	12.85±0.70(Predicted)
Aggregatzustand	Solid
Farbe	White to Off-White
Stabilität	Hygroscopic
InChIKey	NODILNFGTFIURN-IRDSSLPONA-N
LogP	4.730 (est)
CAS Datenbank	11021-13-9(CAS DataBase Reference)

Sicherheit

R-Sätze:	22
S-Sätze:	45-24/25
WGK Germany	3
RTECS-Nr.	LZ5779240
HS Code	29389090

Gefahreninformationscode (GHS)

GINSENOSIDE RB2 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
From the roots of Panax ginseng C.A. Mey.
Verwenden
Ginsenoside Rb2 inhibits the catecholamines secretory responses activated by nicotinic stimulation and by direct membrane depolarization from isolated perfused rat adrenal medulla.
Definition
ChEBI: Ginsenoside Rb2 is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and alpha-L-arabinopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antiviral agent and a hypoglycemic agent. It is a 12beta-hydroxy steroid, a beta-D-glucoside, a disaccharide derivative, a ginsenoside and a tetracyclic triterpenoid. It derives from a hydride of a dammarane.
in vivo

Ginsenoside Rb2 is an antiviral reagent to protect against rotavirus (RV) infection. When various dosages of Ginsenoside Rb2 (25 to 250 mg/kg) are administered 3, 2 or 1 days before virus challenge, treatment with this Ginsenoside at the dosage of 75 mg/kg 3 days before virus infection most effectively reduces rotavirus (RV) -induced diarrhea. In addition, consecutive administration of Ginsenoside Rb2 (75 mg/kg) 3, 2, and 1 day before virus infection is more effective than single administration on day-3. The consecutive administration of Ginsenoside Rb2 also reduces virus titers in the bowels of RV-infected mice^[2].

20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

11021-13-9, GINSENOSIDE RB2 Verwandte Suche:

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