2-O-β-D-Glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-β-D-glucopyranosid

Bezeichnung:2-O-β-D-Glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-β-D-glucopyranosid

CAS-Nr52705-93-8

Englisch Name:Ginsenoside Rd

CBNumberCB1281187

SummenformelC48H82O18

Molgewicht947.15

MOL-Datei52705-93-8.mol

Synonyma

2-O-β-D-Glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-β-D-glucopyranosid

2-O-β-D-Glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-β-D-glucopyranosid physikalisch-chemischer Eigenschaften

Schmelzpunkt	204～206℃
Siedepunkt	1015.6±65.0 °C(Predicted)
Dichte	1.38±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
pka	12.85±0.70(Predicted)
Aggregatzustand	Solid
Farbe	White to Off-White
Stabilität	Hygroscopic
InChIKey	FBFMBWCLBGQEBU-FIKSETHBNA-N
LogP	3.110 (est)
CAS Datenbank	52705-93-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
S-Sätze:	2-45
WGK Germany	3
HS Code	29389090

Gefahreninformationscode (GHS)

Ginsenoside Rd Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S2:Darf nicht in die Hände von Kindern gelangen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax. Structurally, they are steroid glycosides derived from the triterpene squalene. Ginsenoside Rd is a protopanaxadiol which is more abundant in some Panax species (e.g., P. quinquefolium) than others. This ginsenoside has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions. Notably, ginsenoside Rd is converted to other ginsenosides in response to steaming or heating plant materials, leading to loss of these activities.
Chemische Eigenschaften
White to off-white crystals powder
Verwenden
Ginsenoside RD has been shown to attenuate tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after forebrain ischemia. This could be used to counter the risk of developing post-stroke dementia.
Definition
ChEBI: Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as a vulnerary, a neuroprotective agent, an apoptosis inducer, an anti-inflammatory drug, an immunosuppressive agent and a plant metabolite. It is a ginsenoside, a beta-D-glucoside and a tetracyclic triterpenoid. It is functionally related to a (20S)-ginsenoside Rg3.

2-O-β-D-Glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-β-D-glucopyranosid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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