Hydroxyacetone

Bezeichnung:Hydroxyacetone

CAS-Nr116-09-6

Englisch Name:Hydroxyacetone

CBNumberCB0714802

SummenformelC3H6O2

Molgewicht74.08

MOL-Datei116-09-6.mol

Hydroxyacetone physikalisch-chemischer Eigenschaften

Schmelzpunkt	-17 °C (lit.)
Siedepunkt	145-146 °C (lit.)
Dichte	1.082 g/mL at 25 °C (lit.)
Dampfdruck	9.01hPa at 25℃
FEMA	4462 \| HYDROXYACETONE
Brechungsindex	n20/D 1.425(lit.)
Flammpunkt	133 °F
storage temp.	2-8°C
Löslichkeit	water: miscible
pka	13.14±0.10(Predicted)
Aggregatzustand	clear liquid
Farbe	Colorless liquid
Wichte	1.090 (20/4℃)
Geruch (Odor)	at 10.00 % in dipropylene glycol. pungent sweet caramellic ethereal
Geruchsart	caramellic
Wasserlöslichkeit	Miscible with water, alcohol and ether.
Sensitive	Hygroscopic
Merck	14,65
JECFA Number	1945
BRN	605368
Stabilität	Stable. Flammable. Incompatible with strong oxidizing agents, strong acids. Protect from moisture - hygroscopic.
InChIKey	XLSMFKSTNGKWQX-UHFFFAOYSA-N
LogP	0.3 at 25℃
CAS Datenbank	116-09-6(CAS DataBase Reference)
NIST chemische Informationen	2-Propanone, 1-hydroxy-(116-09-6)
EPA chemische Informationen	1-Hydroxyacetone (116-09-6)

Sicherheit

R-Sätze:	2017/10/16
S-Sätze:	23-24/25-5
RIDADR	UN 1224 3/PG 3
WGK Germany	1
RTECS-Nr.	UC2800000
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29144090
Toxizität	mmo-sat 500 mg/plate ABCHA6 47,2461,83

Gefahreninformationscode (GHS)

Hydroxyacetone Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
colourless to yellow liquid
Verwenden
Reagent in organic synthesis; protecting group for the synthesis of peptides.
Verwenden
Hydroxyacetone is a chemical reagent used in various organic chemical reactions. It is a component of the Mannich reaction, amino acid caalyzes direct asymmetric aldol reactions. In the pharmaceutical setting, this compound is used in the synthesis of imidazoles acting as potent and orally active antihypertensive agents.
Verwenden
Hydroxyacetone is used as a reagent in organic chemical reactions. It also serves as a component for Mannich reaction and aldol reactions. It is also used in the syntheses of 2-oxo-propionaldehyde, imidazoles, polyols, acrolein, dyes and skin tanning agents. It yields (R)-1,2-propanediol upon reduction of hydroxyacetone in the presence of a microbial cell catalyst.
Definition
ChEBI: A propanone that is acetone in which one of the methyl hydrogens is replaced by a hydroxy group.
Allgemeine Beschreibung
Hydroxyacetone (Acetol) is important for the manufacture of polyols, acrolein, dyes and skin tanning agents. It undergoes asymmetric reduction to yield (R)-1,2-propanediol in the presence of microbial cell catalyst.
Sicherheitsprofil
Moderately toxic by ingestion. Mutation data reported. An allergen. Implicated in aplastic anemia. A 10 gram dose may be fatal to an adult. skin contact, inhalation, or ingestion can cause asthma, sneezing, irritation of eyes and nose, hives, and eczema. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and fumes.
Synthese
Hydroxyacetone is produced from Bromoacetone plus sodium formate, followed by Methanol hydrolysis of the formed ester. Or by biochemical synthesis from Propylene glycol with sorbose bacterium.

Hydroxyacetone Upstream-Materialien And Downstream Produkte

Hydroxyacetone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

116-09-6, Hydroxyacetone Verwandte Suche:

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