Hydroxylapatit (Ca5(OH)(PO4)3)

Bezeichnung:Hydroxylapatit (Ca5(OH)(PO4)3)

CAS-Nr1306-06-5

Englisch Name:Hydroxyapatite

CBNumberCB2131094

SummenformelCa5HO13P3

Molgewicht502.31

MOL-Datei1306-06-5.mol

Synonyma

Hydroxylapatit (Ca5(OH)(PO4)3)

Hydroxylapatit (Ca5(OH)(PO4)3) physikalisch-chemischer Eigenschaften

Schmelzpunkt	1100 °C(lit.)
Dichte	3.076 g/cm3(Temp: 18 °C)
storage temp.	2-8°C
Löslichkeit	H₂O: 0.3 mg/mL, clear, colorless
Aggregatzustand	solid
Farbe	White
Wasserlöslichkeit	insoluble H2O [MER06]
Merck	13,3500
InChI	InChI=1S/2Ca.H3O4P.H2O/c;;1-5(2,3)4;/h;;(H3,1,2,3,4);1H2/q2*+2;;/p-4
InChIKey	CGMRCMMOCQYHAD-UHFFFAOYSA-J
SMILES	[Ca+2].[Ca+2].P([O-])([O-])([O-])=O.[OH-]
CAS Datenbank	1306-06-5(CAS DataBase Reference)
EPA chemische Informationen	Hydroxylapatite (Ca5(OH)(PO4)3) (1306-06-5)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
RTECS-Nr.	MY8434000
F	3-10
TSCA	Yes
HS Code	28352600
Giftige Stoffe Daten	1306-06-5(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Hydroxyapatite Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Calcium hydroxyapatite has a unique structure in that it is conductive along the hydroxide channels. OH^- ions lie at (1/4/,1/4,1/4) and (3/4/,3/4,3/4) on the c-axis and charge-carrying protons are responsible for the observed conductivities in M10(PO4)6(OH)2. The H⁺ migration between the electroattractive ion (O2) to give molecular H2O in matrix channels carries charge and the resulting conductivity.
The unit cell consists of two triangular prismatic subcells forming a rhombic prism with vertical sides. There are two horizontal mirror planes at the OH levels of 1/4 and 3/4 of the c-axis. In addition, there is a center of inversion exactly in the center of each vertical face of each subcell.
Chemische Eigenschaften
Tricalcium phosphate is an odorless and tasteless powder that is stable in air. Tribasic calcium phosphate consists of a variable mixture of calcium phosphates having the approximate composition of 10CaO·3P2O5·H2O.
Chemische Eigenschaften
white powder
Occurrence
Occurs in nature as the minerals: oxydapatit, voelicherite, whitlockite.
Verwenden
Prosthetic aid (artificial bone and teeth).
Verwenden
Hydroxyapatite and tricalcium phosphate are bioactive ceramic materials and they find applications as bone grafts, fillers and coating material for metal implants.
Verwenden
In the 1970s, it was found that sintered calcium hydroxyapatite, (Ca10(PO4)6(OH)2 (abbreviated as CaHap), possessed excellent biocompatibility and nontoxicity with femur and mandible bones. Since then, CaHap has been used as a biomaterial for artificial teeth and bones and as a filler for cements and polymers. Today, bone fillers made of CaHap are widely used in the medical and dental fields. In the 1980s, it was found that sintered CaHap has a good compatibility with skin tissues. Hence, percutaneous devices based on CaHap have been developed and applications have included continuous ambulatory peritoneal dialysis and intravenous hyperalimentation systems, blood pressure measurement and blood access for nutrition. Recently, many researchers have studied the chemistry of apatites, particularly CaHap, and have found various applications, such as artificial teeth and bones, ion exchangers, adsorbents for chromatography to separate proteins and enzymes, catalysts, ionic conductors, temperature and gas sensors, etc.
Definition
The major constituent of bone and tooth mineral. It is finely divided, crystalline, nonstoichiometric material rich in surface ions (carbonate, magnesium, citrate), which are readily replaced by fluoride ion, thus affording protection to the teeth.
synthetische
The technical product is also known as “bone ash.” Commercial preparation from phosphate rock.
Trademarks
Alveograf (Sterling Winthrop); Periograf (Sterling Winthrop).
Allgemeine Beschreibung
Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.
Flammability and Explosibility
Not classified
Pharmazeutische Anwendungen
Modified hydroxylapatite, also frequently called hydroxyapatite and better known as bone mineral, makes up ～50% of our bones. Hydroxylapatite is a natural form of the mineral calcium apatite, whose formula is usually denoted as Ca₁₀(PO₄)₆(OH)₂. Modifications of hydroxylapatite can also be found in the teeth, and a chemically identical substance is often used as filler for replacement of bones, and so on. Nevertheless, despite similar or identical chemical compositions, the response of the body to these compounds can be quite different.

Hydroxyapatite Upstream-Materialien And Downstream Produkte

Hydroxylapatit (Ca5(OH)(PO4)3) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1306-06-5, Hydroxyapatite Verwandte Suche:

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