2'-Hydroxyacetanilid

Bezeichnung:2'-Hydroxyacetanilid

CAS-Nr614-80-2

Englisch Name:2-Acetamidophenol

CBNumberCB0342159

SummenformelC8H9NO2

Molgewicht151.16

MOL-Datei614-80-2.mol

Synonyma

2'-Hydroxyacetanilid

2'-Hydroxyacetanilid physikalisch-chemischer Eigenschaften

Schmelzpunkt	205-210 °C(lit.)
Siedepunkt	273.17°C (rough estimate)
Dichte	1.2023 (rough estimate)
Brechungsindex	1.5810 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Powder
pka	9.35±0.35(Predicted)
Farbe	Off-white to beige to brown
BRN	607592
Stabilität	Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides.
CAS Datenbank	614-80-2(CAS DataBase Reference)
NIST chemische Informationen	Acetamide, N-(2-hydroxyphenyl)-(614-80-2)
EPA chemische Informationen	2'-Hydroxyacetanilide (614-80-2)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/38-22-36/37/38
S-Sätze:	26-36-37/39
RIDADR	2811
WGK Germany	3
RTECS-Nr.	AE4025000
F	1-8
TSCA	Yes
HazardClass	6.1(b)
PackingGroup	III
HS Code	29242995

Gefahreninformationscode (GHS)

2-Acetamidophenol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.
Verwenden
An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.
synthetische
Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.
Definition
ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
läuterung methode
Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]

2-Acetamidophenol Upstream-Materialien And Downstream Produkte

2'-Hydroxyacetanilid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

614-80-2, 2-Acetamidophenol Verwandte Suche:

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