4-[Bis(p-hydroxyphenyl)methylen]cyclohexa-2,5-dien-1-on

Bezeichnung:4-[Bis(p-hydroxyphenyl)methylen]cyclohexa-2,5-dien-1-on

CAS-Nr603-45-2

Englisch Name:ROSOLIC ACID

CBNumberCB0296269

SummenformelC19H14O3

Molgewicht290.31

MOL-Datei603-45-2.mol

Synonyma

4-[Bis(p-hydroxyphenyl)methylen]cyclohexa-2,5-dien-1-on

4-[Bis(p-hydroxyphenyl)methylen]cyclohexa-2,5-dien-1-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	309°C (decompose)
Siedepunkt	372.4°C (rough estimate)
Dichte	1.2497 (rough estimate)
Brechungsindex	1.4200 (estimate)
storage temp.	Store at room temperature.
Löslichkeit	Practically insoluble in water, benzene; freely soluble in ethanol
Aggregatzustand	Crystalline Powder
Colour Index	43800
pka	6.98(at 25℃)
Farbe	Red-brown to brownish-red
Säure-Base-Indikators(pH-Indikatoren)	6.8(YELLOW)--8.2(RED)
PH	5.0-6.8, yellow to pink
Wasserlöslichkeit	Soluble in alcohol, sodium hydroxide, potassium hydroxide and strong acids. Insoluble in water.
maximale Wellenlänge (λmax)	534.6nm, 479.5nm, 482nm
ε(Extinktionskoeffizient)	≥11000 at 264-270nm in ethanol ≥50000 at 478-486nm in ethanol
Merck	14,881
BRN	2055205
Stabilität	Stable. Incompatible with strong oxidizing agents.
Major Application	electrorheological materials, films patterning, antireflective coatings, thermochromic materials, photoresists, film patterning, recording materials, lithium battery, semiconductors, printing materials, inks, corrosion inhibitors, adhesives, drugs, detecting viable cells, treatment of Alzheimer’s disease
CAS Datenbank	603-45-2
EPA chemische Informationen	2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- (603-45-2)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38-36/38
S-Sätze:	26-36-37/39
WGK Germany	3
TSCA	Yes
HS Code	29145090

Gefahreninformationscode (GHS)

ROSOLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
red crystals or powder
Verwenden
A red coloring medium made from phenol or carbolic acid. It is soluble in alcohol and ether but insoluble in water. When fabrics were steeped in this solution, the color was nonactinic and therefore safe for darkrooms, windows, and doorways. Aurin was also mixed with water-soluble gums and brushed on the backs of collodion and silver bromide gelatin plates as an antihalation layer.
Verwenden
activates heme oxygenase, anti-oxidative stress, inhibits DNA fragmentation
Verwenden
Rosolic acid is used as a pH indicator in the range from 5.0 to 6.8. It acts as an intermediate in the manufacturing dyes. It is involved in the activation of heme oxygenase and in the inhibition of DNA fragmentation. It finds application in the selective isolation of coliform bacteria.
Definition
ChEBI: Aurin is a diarylmethane.
Biologische Aktivität
The transition range of p-Rosolic acid is around pH 6.6-8.0 (Below this pH range it is yellow and above it red).
läuterung methode
It forms green crystals with a metallic luster, but the colour depends on the solvent used. When recrystallised from brine (saturated aqueous NaCl) acidified with HCl, it forms red needles, but when recrystallised from EtO/AcOH, the crystals have a beetle iridescent green colour. It has been recrystallised from Me2CO (although it dissolves slowly), methyl ethyl ketone, 80-95% AcOH and from AcOH/*C6H6. An aqueous KOH solution is golden yellow, and a 70% H2SO4 solution is deep red in colour. An alternative purification is to dissolve this triphenylmethane dye in 1.5% of aqueous NH3, filter, and heat to 70-80o, then acidify with dilute AcOH by adding it slowly with vigorous stirring, whereby the aurin separates as a brick-red powder or as purplish crystals depending on the temperature and period of heating. Filter off the solid, wash it with H2O and a little dilute AcOH, then H2O again. Stir this solid with Et2O to remove any ketones and allow it to stand overnight in the Et2O, then filter and dry it in air then in a vacuum. [Gomberg & Snow J Am Chem Soc 47 202 1925, Baines & Driver J Chem Soc 123 1216 1923, UV: Burawoy Chem Ber 64 462 1941, Beilstein 8 IV 2646.]

ROSOLIC ACID Upstream-Materialien And Downstream Produkte

4-[Bis(p-hydroxyphenyl)methylen]cyclohexa-2,5-dien-1-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

603-45-2, ROSOLIC ACID Verwandte Suche:

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