Hazard
Strong irritant to eyes and skin.
Chemical Properties
white to light yellow crystal powde
Application
2-Furoic acid (FA) is a preservative, acting as a bactericide and fungicide. Some of the applications of 2-furoic acid include:
Synthesis of a single-molecule magnet, Mn11Gd2 based high-nuclearity heterometallic complex.
Synthesis of orally active antidiabetic vanadyl complex, bis(α-furancarboxylato)oxovanadium(IV).
As a ligand in the synthesis of luminescent 4f-3d heterometallic one-dimensional coordination polymers.
Synthesis of biocompatible multifunctional dextran furoate nanospheres.
FA is often used as a starting material for the production of furoate esters.
FA and its derivatives are also used in the production of nylons principally applied in biomedical researches.
Definition
ChEBI: A furoic acid having the carboxylic acid group located at position 2.
Preparation
2-furoic acid can be synthesized by the oxidation of furfural. The reaction was carried out at 45°C with vigorous stirring. The reactant is filtered to recover the catalyst copper oxide, the filtrate is acidified with 50% sulfuric acid to pH 3-2.5, suction filtered, washed with water, and dried to obtain 2-furoic acid.
Flammability and Explosibility
Notclassified
Purification Methods
Crystallise the acid from hot water (charcoal), dry it at 120o for 2hours, then recrystallise it from CHCl3, and again dry it at 120o for 2hours. For use as a standard in volumetric analysis, good quality commercial acid should be crystallised from CHCl3 and dried as above or sublimed at 130-140o/50-60mm or less. [Beilstein 18 I 438, 18 II 265, 18 III/IV 3914, 18/6 V 102.]
