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83-43-2

Name Methylprednisolone
CAS 83-43-2
EINECS(EC#) 201-476-4
Molecular Formula C22H30O5
MDL Number MFCD00010591
Molecular Weight 374.47
MOL File 83-43-2.mol

Chemical Properties

Appearance White to Off-White Crystalline Powder
Melting point  228-237°C (dec.)
alpha  D20 +83° (dioxane)
Boiling point  423.47°C (rough estimate)
density  1.0868 (rough estimate)
refractive index  82 ° (C=1, Dioxane)
storage temp.  0-6°C
solubility  chloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow
form  neat
pka 12.46±0.70(Predicted)
color  White to Off-White
Water Solubility  0.12g/L(25 ºC)
Usage A glucocorticoid
Merck  6111
BRN  2340300
BCS Class 2 or 4?
InChIKey VHRSUDSXCMQTMA-PJHHCJLFSA-N
CAS DataBase Reference 83-43-2(CAS DataBase Reference)
NIST Chemistry Reference 1,4-Pregnadiene-3,20-dione, 11beta,17alpha,21-trihydroxy-6alpha-methyl-(83-43-2)
EPA Substance Registry System 83-43-2(EPA Substance)

Safety Data

Hazard Codes  Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S22:Do not breathe dust .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
WGK Germany  2
RTECS  TU4146000
8-10-23
HS Code  2937290000
Safety Profile
Moderately toxic by intraperitoneal route. A steroid hormone. Human systemic effects include arrhythmias, blood pressure lowering, heart rate changes, increased body temperature, pulse rate increase, respiratory depression. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazardous Substances Data 83-43-2(Hazardous Substances Data)

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