ChemicalBook CAS DataBase List 149-44-0

149-44-0

Name	RONGALITE
CAS	149-44-0
EINECS(EC#)	205-739-4
Molecular Formula	CH3NaO3S
MDL Number	MFCD00040426
Molecular Weight	118.09
MOL File	149-44-0.mol

Chemical Properties

Appearance	solid
Melting point	~120 °C (dec.)
density	1.744[at 20℃]
vapor pressure	0.003Pa at 20℃
Fp	>100℃
storage temp.	Inert atmosphere,Room Temperature
solubility	H₂O: 50 mg/mL, clear, colorless
form	Solid
color	White to Off-White
Odor	Mild garlic odor
PH	9.5-10.5
Stability:	Stable. Incompatible with strong oxidizing agents.
Water Solubility	soluble H2O, alcohol [HAW93]
Merck	8620
Cosmetics Ingredients Functions	REDUCING
LogP	-3.4 at 22℃
EPA Substance Registry System	Sodium sulfoxylate formaldehyde (anhydrous) (149-44-0)

Safety Data

Symbol(GHS)	GHS07,GHS08
Signal word	Warning
Hazard statements	H341-H315-H319-H335
Precautionary statements	P280-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes	Xi,Xn
Risk Statements	36/37/38-68-31 less more
Safety Statements	26-36-36/37 less more
WGK Germany	1
RTECS	PB0380000
TSCA	Yes
REACH Registrations	Active
HS Code	2930909899
Hazardous Substances Data	149-44-0(Hazardous Substances Data)

Raw materials And Preparation Products

Hazard Information

Chemical Properties

solid

Uses

Pharmaceutic aid (preservative).

Production Methods

Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.

Purification Methods

It crystallises from H2O as the dihydrate and decomposes at higher temperatures. Store it in a closed container in a cool place. It is insoluble in EtOH and Et2O and is a good reducing agent. [X-ray structure: Tuter J Chem Soc 3064 1955.] Note that this compound {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn. [Beilstein 1 IV 3052.]

Flammability and Explosibility

Nonflammable

Pharmaceutical Applications

Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.

Safety

The toxicological properties of sodium formaldehyde sulfoxylate have not been fully investigated. However, it is used in the formulation of injection products at a level to 0.1% w/v in the final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by ingestion, and when heated to decomposition it emits toxic fumes of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg

storage

Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).

Incompatibilities

Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.

Regulatory Status

Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Spectrum Detail

Supplier

J & K SCIENTIFIC LTD.

Telephone18210857532 18210857532

Websitehttps://www.jkchemical.com

Meryer (Shanghai) Chemical Technology Co., Ltd.

Telephone4006356688 18621169109

Websitehttp://www.x-labseek.com/

Alfa Aesar

Telephone400-6106006

Websitehttp://chemicals.thermofisher.cn

TCI (Shanghai) Development Co., Ltd.

Telephone021-67121386

Websitehttps://www.tcichemicals.com/CN/zh/

Energy Chemical

Telephone021-021-58432009 400-005-6266

Websitehttp://www.energy-chemical.com

Beijing Ouhe Technology Co., Ltd

Telephone13552068683 13522913783

Websitehttp://www.ouhetech.cn/

Shanghai Hanhong Scientific Co.,Ltd.

Telephone021-54306202 13764082696

Websitehttps://www.hanhongsci.com

Chemsky（shanghai）International Co.,Ltd.

Telephone021-50135380

Websitehttp://www.shchemsky.com

Shandong Xiya Chemical Co., Ltd

Telephone13355009207 13355009207

Websitehttp://www.xiyashiji.com

Sichuan Kulinan Technology Co., Ltd

Telephone400-1166-196 18981987031

Websitehttp://www.hx-r.com/

Tianjin heowns Biochemical Technology Co., Ltd.

Telephone400 638 7771

Websitehttp://www.heowns.com

Maya High Purity Chemicals

Telephone+86 (573) 82222445 (0)18006601000 452520369

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm

Spectrum Chemical Manufacturing Corp.

Telephone021-021-021-67601398-809-809-809 15221380277

Websitehttps://www.spectrumchemical.com/OA_HTML/index.jsp?minisite=10020&respid=22372&language=US

Wuhan Fortuna Chemical Co., Ltd

Telephone027-59207852 13308628970

Websitehttp://www.fortunachem.cn

Chengdu Ai Keda Chemical Technology Co., Ltd.

Telephone4008-755-333 18080918076

Websitehttp://www.aikeshiji.com

Shanghai civi chemical technology co.,Ltd

Telephone86-21-34053660

Websitehttp://www.labgogo.com

Shanghai T&W Pharmaceutical Co., Ltd.

Telephone+86 21 61551611

Websitehttp://www.trustwe.com

9ding chemical ( Shanghai) Limited

Telephone4009209199

Websitehttp://www.9dingchem.com

1of4

Related Products

Send Inquriy