7558-79-4

Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Concentration	0.50%	1%	2%	5%	10%	15%	20%	25%	30%	40%	50%
mS/cm	4.2	8.7	15.6	31.4	–	–	–	–	–	–	–

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm³; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm³ at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm³; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm³; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.

Disodium phosphate is anhydrous or contains two molecules of water of hydration

ChEBI: Disodium hydrogenphosphate is a sodium phosphate.

Nonflammable

Sodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.

Crystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.

The initial threshold screening level (ITSL) for disodium hydrogen phosphate is 10 μg/m3 (annual averaging time) based on the Environmental Protection Agency’s (EPA’s) reference concentration (RfC) value for phosphoric acid (EPA, 1995). The ITSL value was established by AQD on August 1, 2012 (MDEQ, 2012; see attached).