594-44-5

clear light brownish to pinkish-purple liquid

Chloroethylsulfone was used in discovery of a selective inhibitor of oncogenic B-raf kinase with potent antimelanoma activity.

Ethanesulfonyl chloride can make sulfonyl-substituted imides, methide lithium salts, and pentafluoroethanesulfonyl fluoride, a fluorinated surfactant. It is an intermediate in synthesizing new, low-cost, non-fluorinated, sulfonyl-substituted imide and methide lithium salts and an intermediate in preparing the fluorinated surfactant pentafluoroethanesulfonyl fluoride.

Journal of the American Chemical Society, 61, p. 2548, 1939 DOI: 10.1021/ja01878a085