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YELLOW TO BROWN CRYSTALLINE POWDER

2-Bromo-5-nitrothiazole is used as a building block. It is used as an intermediate to produce other chemicals.

The reaction of 2-Bromo-5-nitrothiazole with weakly basic secondary aliphatic amines produces the expected 2-amino product from nucleophilic substitution of bromine. However, the reaction of isomeric 5-bromo-2-nitrothiazole with such amines produces the expected mixture of the 5-amino product and the 2-amino 5-nitrothiazole rearrangement product.