Chemical Properties
White Crystalline Solid
Usage
A neuroprotective agent. A glutamate release inhibitor. An anticonvulsant
Usage
A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.
Usage
anticonvulsant, glutamate release inhibitor, anti-ALS
Biological Activity
Novel psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Riluzole is able to act as a glutamate release inhibitor, blocks voltage-dependent Na + channels and inhibits GABA uptake by striatal synaptosomes.
Originator
Rhone-Poulenc Rorer (France)
Uses
A neuroprotective agent. A glutamate release inhibitor. An anticonvulsant
Uses
A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.
Uses
anticonvulsant, glutamate release inhibitor, anti-ALS
Uses
Labeled Riluzole, intended for use as an internal standard for the quantification of Riluzole by GC- or LC-mass spectrometry.
Definition
ChEBI: Riluzole is a member of benzothiazoles.
Brand name
Rilutek (Sanofi Aventis).
Biochem/physiol Actions
Glutamate release inhibitor; anticonvulsant