13030-09-6

56-86-0

100-51-6

1676-73-9

13030-09-6

The general procedure for the synthesis of L-glutamic acid-5-benzyl ester and (S)-4-amino-5-(benzyloxy)-5-oxopentanoic acid from L-glutamic acid and benzyl alcohol was as follows: under typical reaction conditions, 6.8 mmol L-glutamic acid, 10.2 mmol benzyl alcohol (the molar ratio of L-glutamic acid to benzyl alcohol was 1:1.5), and 0.68 mmol CuCl2 were added to a 50 mL single-necked reaction flask. The reaction mixture was stirred at 60 °C for 2 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature, followed by subsequent analysis.