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Мивакурия хлорид
- английское имяMivacurium chloride
- CAS №106861-44-3
- CBNumberCB7218031
- ФормулаC58H80ClN2O14+
- мольный вес1064.73
- EINECS643-006-4
- номер MDLMFCD00867767
- файл Mol106861-44-3.mol
химическое свойство
альфа | 20D -62.7° (c = 1.9 in water) |
температура хранения | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
растворимость | DMSO: Soluble; Water: Soluble |
форма | A solid |
цвет | White to off-white |
Стабильность | Hygroscopic |
ИнЧИКей | KFWHZSUNFAPZPW-NVIAPQDINA-M |
FDA UNII | 600ZG213C3 |
Код УВД | M03AC10 |
рисовальное письмо(GHS)
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рисовальное письмо(GHS)
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сигнальный язык
опасность
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вредная бумага
H301:Токсично при проглатывании.
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оператор предупредительных мер
P264:После работы тщательно вымыть кожу.
P270:При использовании продукции не курить, не пить, не принимать пищу.
P301+P310:ПРИ ПРОГЛАТЫВАНИИ: Немедленно обратиться за медицинской помощью. Прополоскать рот.
P405:Хранить в недоступном для посторонних месте.
P501:Удалить содержимое/ контейнер на утвержденных станциях утилизации отходов.
Мивакурия хлорид химические свойства, назначение, производство
Описание
Mivacurium chloride,a mixture of three stereoisomers, is an intravenously administered, short-acting skeletal muscle relaxant introduced as an adjunct to general anesthesia. Structurally mivacurium chloride is closely related to doxacurium chloride introduced in 1991 by Wellcome as a muscle relaxant. It is a nondepolarizing neuromuscular blocking agent reportedly with a shorter duration of action and a more rapid rate of spontaneous recovery than other nondepolarizing agents. In extensive clinical trials mivacurium chloride was well tolerated with few side effects.Химические свойства
Off-White SolidИспользование
Non-depolarizing neuromuscular blocking agent. Muscle relaxant (skeletal)Биологические функции
Mivacurium chloride (Mivacron) is a newer agent that is chemically related to atracurium. The primary mechanism of inactivation is hydrolysis by plasma cholinesterase. Although it is useful for patients with renal or hepatic disease, some caution is warranted, since these individuals may have reduced plasma cholinesterase as a result of the disease.Mivacurium has an onset of action (1.8 minutes) and duration of effect (20 minutes) only twice that of succinylcholine, and in this respect, it is the most similar to succinylcholine of all of the nondepolarizing agents.Общее описание
Mivacurium chloride, 1,2,3,4-tetrahydro-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)isoquinolinium chloride, (E)-4-octandioate (Mivacron), is a mixture of three stereoisomers,the trans-trans, cis-trans, and cis-cis diesters, each ofwhich has neuromuscular blocking properties. The cis-cisisomer is about one tenth as potent as the other isomers.Mivacurium chloride is a short-acting nondepolarizing drugused as an adjunct to anesthesia to relax skeletal muscle.The drug is hydrolyzed by plasma esterases, and it is likelythat anticholinesterase agents used as antidotes could prolongrather than reverse the effects of the drug.Мивакурия хлорид запасные части и сырье
Мивакурия хлорид поставщик
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