L(+)-винная кислота
- английское имяL(+)-Tartaric acid
- CAS №87-69-4
- CBNumberCB8212874
- ФормулаC4H6O6
- мольный вес150.09
- EINECS201-766-0
- номер MDLMFCD00064207
- файл Mol87-69-4.mol
химическое свойство
| Температура плавления | 170-172 °C(lit.) |
| альфа | 12 º (c=20, H2O) |
| Температура кипения | 191.59°C (rough estimate) |
| плотность | 1.76 |
| плотность пара | 5.18 (vs air) |
| давление пара | <5 Pa (20 °C) |
| FEMA | 3044 | TARTARIC ACID (D-, L-, DL-, MESO-) |
| показатель преломления | 12.5 ° (C=5, H2O) |
| Fp | 210 °C |
| температура хранения | Store at +5°C to +30°C. |
| растворимость | H2O: soluble1M at 20°C, clear, colorless |
| форма | Solid |
| пка | 2.98, 4.34(at 25℃) |
| цвет | White or colorless |
| РН | 3.18(1 mM solution);2.55(10 mM solution);2.01(100 mM solution); |
| Запах | at 100.00 %. odorless |
| Odor Type | odorless |
| оптическая активность | [α]20/D +13.5±0.5°, c = 10% in H2O |
| Растворимость в воде | 1390 g/L (20 ºC) |
| Номер JECFA | 621 |
| Мерк | 14,9070 |
| БРН | 1725147 |
| Диэлектрическая постоянная | 35.9（-10℃） |
| Стабильность | Stable. Incompatible with oxidizing agents, bases, reducing agents. Combustible. |
| ИнЧИКей | FEWJPZIEWOKRBE-JCYAYHJZSA-N |
| LogP | -1.43 |
| FDA 21 CFR | 184.1099; 582.1099; 582.6099 |
| Вещества, добавляемые в пищу (ранее EAFUS) | TARTARIC ACID, L |
| Специальный комитет по веществам GRAS | L(+)-tartaric acid |
| Справочник по базе данных CAS | 87-69-4(CAS DataBase Reference) |
| FDA UNII | W4888I119H |
| Справочник по химии NIST | Butanedioic acid, 2,3-dihydroxy- [r-(r*,r*)]-(87-69-4) |
| Система регистрации веществ EPA | Tartaric acid (87-69-4) |
больше
| Коды опасности | Xi | |||||||||
| Заявления о рисках | 36/37/38-41 | |||||||||
| Заявления о безопасности | 26-36-37/39-36/37/39 | |||||||||
| WGK Германия | 3 | |||||||||
| RTECS | WW7875000 | |||||||||
| Температура самовоспламенения | 797 °F | |||||||||
| Примечание об опасности | Irritant | |||||||||
| TSCA | Yes | |||||||||
| кода HS | 29181200 | |||||||||
| NFPA 704: |
|
рисовальное письмо(GHS)
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рисовальное письмо(GHS)
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сигнальный язык
опасность
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вредная бумага
H318：При попадании в глаза вызывает необратимые последствия.
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оператор предупредительных мер
P280：Использовать перчатки/ средства защиты глаз/ лица.
P305+P351+P338：ПРИ ПОПАДАНИИ В ГЛАЗА: Осторожно промыть глаза водой в течение нескольких минут. Снять контактные линзы, если Вы ими пользуетесь и если это легко сделать. Продолжить промывание глаз.
L(+)-винная кислота химические свойства, назначение, производство
Химические свойства
Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder. It is odorless, with an extremely tart taste. L-(+)-Tartaric Acid is a naturally occurring chemical compound found in berries, grapes and various wines. It provides antioxidant properties and contributes to the sour taste within these products.Определение
ChEBI: L-tartaric acid is a tetraric acid that is butanedioic acid substituted by hydroxy groups at positions 2 and 3. It is a conjugate acid of a L-tartrate(1-). It is an enantiomer of a D-tartaric acid.Методы производства
Tartaric acid occurs naturally in many fruits as the free acid or in combination with calcium, magnesium, and potassium.Commercially, L-(＋)-tartaric acid is manufactured from potassium tartrate (cream of tartar), a by-product of wine making. Potassium tartrate is treated with hydrochloric acid, followed by the addition of a calcium salt to produce insoluble calcium tartrate. This precipitate is then removed by filtration and reacted with 70% sulfuric acid to yield tartaric acid and calcium sulfate.
Общее описание
Tartaric Acid belongs to the group of carboxylic acids, and is abundantly found in grapes and wine. It is widely used in drugs, food, and beverage industry.Фармацевтические приложения
Tartaric acid is used in beverages, confectionery, food products, and pharmaceutical formulations as an acidulant. It may also be used as a sequestering agent and as an antioxidant synergist. In pharmaceutical formulations, it is widely used in combination with bicarbonates, as the acid component of effervescent granules, powders, and tablets.Tartaric acid is also used to form molecular compounds (salts and cocrystals) with active pharmaceutical ingredients to improve physicochemical properties such as dissolution rate and solubility.
Профиль безопасности
Moderately toxic by intravenous route. Mildly toxic by ingestion. Reaction with silver produces the unstable silver tartrate. When heated to decomposition it emits acrid smoke and irritating fumes.Безопасность
Tartaric acid is widely used in food products and oral, topical, and parenteral pharmaceutical formulations. It is generally regarded as a nontoxic and nonirritant material; however, strong tartaric acid solutions are mildly irritant and if ingested undiluted may cause gastroenteritis.An acceptable daily intake for L-(＋)-tartaric acid has not been set by the WHO, although an acceptable daily intake of up to 30 mg/kg body-weight for monosodium L-(＋)-tartrate has been established.
LD50 (mouse, IV): 0.49 g/kg
хранилище
The bulk material is stable and should be stored in a well-closed container in a cool, dry place.Несовместимости
Tartaric acid is incompatible with silver and reacts with metal carbonates and bicarbonates (a property exploited in effervescent preparations).Регуляторный статус
GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (IM and IV injections; oral solutions, syrups and tablets; sublingual tablets; topical films; rectal and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.L(+)-винная кислота запасные части и сырье
сырьё
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L(+)-винная кислота поставщик
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