PEANUT OIL

Химические свойства

Peanut oil is a colorless or pale yellow-colored liquid that has a faint nutty odor and a bland, nutty taste. At about 3°C it becomes cloudy, and at lower temperatures it partially solidifies.

Использование

peanut oil is utilized as a skin softener, emulsifier, and emollient. It can also be used as a substitute for more expensive oils such as almond and olive in cosmetic creams. Peanut oil has a higher vitamin A, vitamin e, and nicotinic acid content than other nut oils. It is obtained by pressing the seed kernels.

Методы производства

Refined peanut oil is obtained from the seeds of Arachis hypogaea Linne′ (Fam. Leguminosae). The seeds are separated from the peanut shells and are expressed in a powerful hydraulic press. The crude oil has a light yellow to light brown color, and is then purified to make it suitable for food or pharmaceutical purposes. A suitable antioxidant may be added.

Общее описание

Pale yellow oily liquid with a weak odor of peanuts. Floats on water. Contains principally glycerides of oleic and linoleic acids.

Реакции воздуха и воды

Insoluble in water.

Профиль реактивности

PEANUT OIL react with acids to liberate heat. Heat is also generated by interaction with caustic solutions. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Flammable hydrogen is generated by mixing with alkali metals and hydrides. React slowly with oxygen in the air to become rancid.

Угроза здоровью

None-is a food.

Фармацевтические приложения

Peanut oil is used as an excipient in pharmaceutical formulations primarily as a solvent for sustained-release intramuscular injections. It is also used as a vehicle for topical preparations and as a solvent for vitamins and hormones. In addition, it has been part of sustained-release bead formulations,nasal drug delivery systems,and controlled-release injectables.
Therapeutically, emulsions containing peanut oil have been used in nutrition regimens, in enemas as a fecal softener, and in otic drops to soften ear wax. It is also administered orally, usually with sorbitol, as a gall bladder evacuant prior to cholecystography.
Peanut oil is also widely used as an edible oil.

Профиль безопасности

A human skin irritant and mild allergen. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Combustible when exposed to heat or flame; can react with oxidizing materials. Slight spontaneous heating. To fight fire, use CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes

Безопасность

Peanut oil is mildly laxative at a dosage of 15–60mL orally or of 100–500mL rectally as an enema.
Adverse reactions to peanut oil in foods and pharmaceutical formulations have been reported extensively.These include severe allergic skin rashes and anaphylactic shock following consumption of peanut butter.Some workers have suggested that the use in infancy of preparations containing peanut oil, including infant formula and topical preparations, is associated with sensitization to peanut, with a subsequent risk of hypersensitivity reactions, and that such products should therefore be avoided or banned.However, the role of pharmaceutical preparations in later development of hypersensitivity is disputed since such preparations contain highly refined peanut oil that should not contain the proteins associated with allergic reactions in susceptible individuals.
Peanut oil is harmful if administered intravenously and it should not be used in such formulations.

хранилище

Peanut oil is an essentially stable material.However on exposure to air it can slowly thicken and may become rancid. Solidified peanut oil should be completely melted and mixed before use. Peanut oil may be sterilized by aseptic filtration or by dry heat, for example, by maintaining it at 150°C for 1 hour.
Peanut oil should be stored in a well-filled, airtight, lightresistant container, at a temperature not exceeding 40°C. Material intended for use in parenteral dosage forms should be stored in a glass container.

Несовместимости

Peanut oil may be saponified by alkali hydroxides.

Регуляторный статус

Included in the FDA Inactive Ingredients Database (IM injections, topical preparations, oral capsules, and vaginal emulsions). Included in parenteral and nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.