Carboxyethylgermanium sesquioxide

Описание

Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.

Использование

antifungal and antiseptic

Общее описание

Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.

Профиль безопасности

Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.