Эмодин

Химические свойства

red-orange powder

Использование

Emodin has been used:

• to investigate its regulatory mechanisms on lipopolysaccharide (LPS)-induced inflammatory injury in myocarditis
• as a reference standard for the development and validation of high performance liquid chromatography (HPLC)-photodiode array (PDA) assay method
• to inhibit Tau aggregation
• for direct binding assay

Общее описание

Orange needles or powder.

Реакции воздуха и воды

Insoluble in water.

Профиль реактивности

Emodin may be sensitive to prolonged exposure to light. Probably a weak acid due to the phenolic functional groups.

Угроза здоровью

ACUTE/CHRONIC HAZARDS: When heated to decomposition Emodin emits acrid smoke and irritating fumes.

Пожароопасность

Flash point data for Emodin are not available; however, Emodin is probably combustible.

Биологическая активность

Naturally occurring anthraquinone that displays a range of biological activities. Exhibits anti-inflammatory, antitumor and neuroprotective effects.

Методы очистки

Archin forms orange needles from EtOH, Et2O, *C6H6, toluene or pyridine. It sublimes above 200o at 12mm. [Tutin & Clewer J Chem Soc 99 946 1911, IR: Bloom et al. J Chem Soc 178 1959, UV: Birkinshaw Biochem J 59 495 1955, Raistrick Biochem J 34 159 1940.] 1R,2S-(-)Ephedrine see (-)-ephedrine (1R,2S-2-methylamino-1-phenylpropanol) in “Miscellaneous” in Chapter 6.