Dodecyl gallate

Описание

This gallate ester (E 310) is an antioxidant added to foods and cosmetics to prevent oxidation of unsaturated fatty acids. Cases have been reported in workers in the food industry, gallate being contained in margarine. It is also present in washing powder.

Химические свойства

white to cream powder

Использование

Dodecyl Gallate is an antioxidant used in cream cheese, instant mashed potatoes, margarine, fats, and oils.

Общее описание

Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers.

Контактные аллергены

This gallic acid ester (E 310) is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were reported in workers of the food industry, gallate being contained in margarine, and from washing powder.

Профиль безопасности

Poison by ingestion and inhalation. Moderately toxic by skin contact. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. A pesticide. When heated to decomposition it emits very toxic fumes of NOx.

Канцерогенность

In a 2-year feeding study, with the administration of up to 5 mg/kg of feed to rats, no increase in tumor incidence was noted . In female mice, a dermal injection of dodecyl gallate (100 nmol in 0.2mL acetone) inhibits the formation of skin carcinomas and papillomas induced by the tumor promoter phorbol myristate and the initiator 7,12-dimethylbenz[a]anthracene .