aladdin 阿拉丁 S131899 SB-203580,p38 MAPK抑制剂 152121-47-6 ≥98%(HPLC)

中文名：SB-203580,p38 MAPK抑制剂

英文名：SB-203580

英文别名：152121-47-6|SB 203580|SB-203580|SB203580|4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole|Adezmapimod|4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine|4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-

纯度：≥98%(HPLC)

货号：S131899

包装：100mg、5mg、25mg

Cas号：152121-47-6

存储温度：-20°C储存

产品介绍：

SB203580是一种p38 MAPK抑制剂，在THP-1细胞中IC50为0.3-0.5 μM，对SAPK3(106T)和SAPK4(106T)选择性低10倍，且阻断PKB磷酸化，IC50为3-5 μMMDCK cells were treated with SB 203580 to study the role of MAPK signaling in inducing hypertonicity of cell membrane and potassium depletion.¹⁶ It was used to inhibit MAPK signaling in mouse cortical neurons¹⁷ and human hepatocellular carcinoma cell lines.¹⁸

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