🌟 Sugammadex Sodium (CAS 343306-79-6) - Product Overview
Sugammadex Sodium is a synthetic γ-cyclodextrin derivative (molecular formula: C₇₂H₁₀₄Na₈O₄₈S₈, MW: 2178.01) designed to rapidly reverse rocuronium- or vecuronium-induced neuromuscular blockade during surgical anesthesia. It acts as a selective neuromuscular reversal agent, binding tightly to muscle relaxants to enable swift recovery of muscle function and reduce postoperative complications. With ≥99.5% HPLC purity and stability at 2-8°C, it is a critical pharmaceutical-grade API for anesthesia management.
🔑 Key Advantages
✔️ Rapid Recovery: Achieves neuromuscular recovery in ≤3.6 minutes with a 2.5 mg/kg dose.
✔️ High Selectivity: Specifically targets rocuronium/vecuronium without affecting acetylcholine levels.
✔️ Water Solubility: >50 mg/mL, ideal for injectable formulations.
✔️ Stability: Maintains integrity under inert atmospheric storage conditions.
📋 Applications
Surgical Anesthesia: Primary use for reversing neuromuscular blockade post-surgery.
Clinical Antidote: Essential for emergency reversal of muscle relaxants.
Research: Studies on neuromuscular physiology and anesthesia optimization.
🏅 Quality & Compliance
Complies with USP/EP pharmacopeial standards.
Rigorously tested via HPLC, GC, and NMR for batch consistency.
Manufactured under GMP guidelines in ISO-certified facilities.
📈 Market Insight
The global neuromuscular blockade reversal market is projected to grow significantly by 2030, driven by rising surgical volumes and demand for precision anesthesia solutions. Sugammadex Sodium remains a gold-standard agent due to its efficacy and safety profile.
China
