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Quinine

Product NameQuinine

CAS130-95-0

MFC20H24N2O2

MW324.42

EINECS205-003-2

MOL File130-95-0.mol

Chemical Properties

Melting point 173-175 °C(lit.)
alpha  -172 º (c=1, EtOH)
Boiling point 462.75°C (rough estimate)
Density  1.1294 (rough estimate)
refractive index  1.6250 (estimate)
Flash point >110°C (>230°F)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  H2O: soluble
pka 8.52(at 25℃)
form  Crystalline Powder
color  White
PH 9.0 (0.5g/l, H2O, 20℃)
PH Range Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)
optical activity [α]25/D 165°, c = 2 in ethanol
Water Solubility  slightly soluble
Sensitive  Light Sensitive
Hydrolytic Sensitivity 2: reacts with aqueous acid
Merck  14,8061
BRN  91867
Major Application Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system
CAS DataBase Reference 130-95-0(CAS DataBase Reference)
NIST Chemistry Reference Quinine(130-95-0)
EPA Substance Registry System Quinine (130-95-0)

Safety Information

Hazard Codes  Xn,Xi
Risk Statements  36/37/38-42/43-22-20/22-20/21/22-36/38
Safety Statements  22-26-36/37-45-37/39-36-7
RIDADR  1544
WGK Germany  3
RTECS  VA6020000
8
HazardClass  6.1(b)
PackingGroup  III
HS Code  29392110
Hazardous Substances Data 130-95-0(Hazardous Substances Data)
Toxicity Antimalarial still used primarily for treatment of plasmodium resistant to synthetic antimalarials. Also used as antipyretic for colds, influenza, and cramp; quinine may have toxic effects on the eye, apparently due to an immune reaction, and may also affect male reproductive capacity.

MSDS

Usage And Synthesis

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