Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Heterocyclic compound >  Quinoline compounds >  Nitroxoline

Nitroxoline

Basic information Safety Related Supplier
Nitroxoline Basic information
Nitroxoline Chemical Properties
  • Melting point:181-183 °C(lit.)
  • Boiling point:325.64°C (rough estimate)
  • Density 1.3907 (rough estimate)
  • refractive index 1.5570 (estimate)
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • solubility alcohol: very slightly soluble
  • pka2.55±0.10(Predicted)
  • Merck 14,6655
  • NIST Chemistry Reference8-Hydroxy-5-nitroquinoline(4008-48-4)
Safety Information
  • Hazard Codes T,Xi,Xn
  • Risk Statements 23/24/25-36/37/38-22/24/25-20/21/22
  • Safety Statements 26-36-45
  • RIDADR UN 2811 6.1/PG 3
  • WGK Germany 3
  • RTECS VC8225000
  • Hazard Note Toxic/Irritant
  • HazardClass 6.1
  • PackingGroup III
  • HS Code 29334900
  • ToxicityLD50 oral in rat: 510mg/kg
MSDS
Nitroxoline Usage And Synthesis
  • Chemical Propertiesochre-yellow to brownish crystalline powder
  • Usesantibacterial
  • Uses5-Nitro-8-hydroxyquinoline is an antimicrobial agent used for the treatment of urinary tract infection. 5-Nitro-8-hydroxyquinoline is also a potent and reversible inhibitor of cathepsin B. 5-Nitro-8-h ydroxyquinoline has been shown to have anti-cancer activity.
  • DefinitionChEBI: A monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5.
  • brand name5-nitrok;Dovenix;Entercol;Enterocol;Isinok;Nicene;Nikinol;Nikopet;Noxine;Trodax;Uro-coli.
  • World Health Organization (WHO)Nitroxoline, a urinary antiseptic, was introduced in the mid-1960s. By the early 1970s long-term animal studies revealed the development of cataracts in rats and, although no serious adverse effects had been reported in man, the drug was withdrawn in at least two countries. Preparations containing nitroxoline remain widely available.
Nitroxoline(4008-48-4)Related Product Information
NitroxolineSupplierMore
  • Company Name:Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. Gold
  • Tel:18678026865 1867-8026865-
  • Email:sdfantai@163.com;sdfantai@163.com
  •  
  • Company Name:Shandong Chenyi Environmental Protection Technology Co., Ltd Gold
  • Tel:18560179988 0531-83179999-
  • Email:chenyihbao@163.com;chenyihbao@163.com
  •  
  • Company Name:NANJING GM LABORTORY APPARATUS.,LTD Gold
  • Tel:17366332767 025-58277916-
  • Email:GM58277916@163.com
  •  
  • Company Name:Shandong Xibang Biological Technology Development Co. LTD Gold
  • Tel:15063661551 0536-3611186-
  • Email:196056703@qq.com
  •  
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
  •